Tottenham midfielder Mousa Dembele is set to join Chinese club Guangzhou R&F as he will be travelling to Hong Kong to undergo a medical.Skysports reports Spurs have been receiving several offers from China as Super League side Beijing Sinobo Guoan tabled an offer which the club accepted but an acceptable offer has now been made by Guangzhou R&FThe Belgium international has spent six-and-a-half-years with Tottenham and it is likely that this window will bring an end to his stay with the North London side as his contract expires at the end of the season.Mousa Dembele backs Gareth Bale’s shock China move Andrew Smyth – July 28, 2019 Mousa Dembele believes his former Tottenham team-mate Gareth Bale will find things “easy” in China and hopes the Real Madrid player makes the move.Dembele has not played for Spurs since November due to an ankle injury and has reportedly been keen on a move to China since the summer.It is still unclear who will replace Dembele at Spurs but the club have been monitoring the likes of Tanguy Ndombele, Abdoulaye Doucoure and Donny van de Beek.Tottenham hope to retain their top four position this season.
TV and Movies Everyone in kings landing. #GameofThrones pic.twitter.com/pnf4uB8Ua4— Danish Khurshid (@ShahDanish_) May 13, 2019 The Mad Queen? HBO It’s been an up and down season for Game of Thrones. A dragon was killed in ways that frustrated and annoyed everyone, everyone got extremely angry when Jon Snow didn’t pet Ghost and then the internet found a coffee cup on set and went buck wild.This episode was all about the insane carnage.OK, goes without saying but…It started early with the burning of Varys. And the burning just didn’t stop.The question going in was simple: Was Dany about to become the Mad Queen, or was it all just a big swerve?Yeah, they answered that pretty definitively. Daenerys Targaryen basically set all of King’s Landing on fire. The Bells rang out for surrender but Dany wasn’t trying to hear that noise. Me, The entire episode #GameOfThrones pic.twitter.com/Ss3l6yx4cT— 𝑨𝒓𝒊 𝐒𝐭𝐚𝐫𝐤 (@solangev_a) May 13, 2019 Bran chilling in Winterfell while Daenerys kills everyone: #GameofThrones pic.twitter.com/KQKBLoAGL1— MWV Highlights (@MWV_Highlights) May 13, 2019 Waiting all these years for main character deaths and we see stone crushing them. #GameofThrones pic.twitter.com/Vh76HcdKBG— Shay (@shayycs) May 13, 2019 6:20 I’ve been working very very hard not to do any spoilers but I will say this: I look forward to reading the book and seeing how #GameofThrones really ended.Because this isn’t it.— Steve Spohn (@stevenspohn) May 13, 2019 Drogon after that episode #GameofThrones pic.twitter.com/hUQtS8Btya— church (@COFFINBORNEGOD) May 13, 2019 See all the Game of Thrones season 8 photos Jon Snow halfway through the episode#GameofThrones pic.twitter.com/eSVnbqEADW— T (@I_Gas247) May 13, 2019 All the haters should just go to sleep. That episode was phenomenal. I’m sick of people’s negativity. Get outta here. #GameOfThrones pic.twitter.com/XBDqjDBJWi— Seth Nelson (@RealSethNelson) May 13, 2019 Now playing: Watch this: Soldiers: The bells are ringing! Danny: Are they though? #GameofThrones pic.twitter.com/8ieNiW10BM— Ron Snow (@RonMorrisse) May 13, 2019 It’s a nice little throwback to this: #gameofthrones me: dany won’t murder all these innocent people they rang the bells we’re all good!!!dany: (: dracarys me: pic.twitter.com/OVGjw8wT8S— madz🦋✨💫 (@maddyackerburg) May 13, 2019 Dany after this episode#GameofThrones pic.twitter.com/3u935UflEp— Jonas Ryan (@jonasryan_) May 13, 2019 Us spending the last 10 years of our lives emotionally attached to a TV show only for the writers to just give us the worst ending possible. #GameofThrones pic.twitter.com/CNcmVm4H0S— Caleb (@CalebKesler) May 13, 2019 Tags This was from a Season 4 promo. We all thought it was snow.. little did we know it was ash. #GameOfThrones pic.twitter.com/ieVUaaQPV8— Chris Brown (@chriscbrown) May 13, 2019 36 #GameofThrones #GoTAll the parents who named their daughter khaleesi or dany: pic.twitter.com/qf9EwTp6Ha— Ali (@Ali_Givenchy) May 13, 2019 The writers destroying the entire show in the final season #GameOfThrones pic.twitter.com/vXtJgAyDTs— Valentina ☕️ (@ValsCappuccino) May 13, 2019 Comments Share your voice Jon, Sansa and Tyrion plotting to kill Danny next week: #GameOfThrones pic.twitter.com/lCBVvJ9EDF— Ebony Barzilay (@o_hon_ey) May 13, 2019 187 Photos That game of thrones episode was wild— timthetatman (@timthetatman) May 13, 2019 Thoughts? Well, Mad Queen Dany is bad and everyone should feel bad. Very disappointed we spent a decade watching a really great female leader emerge, with a very cool and consistent “break the wheel” message only to have it completely turned around at the last, crucial minute. Not sure it entirely made sense, but I sure had a lot of fun watching it all unfold.I do get the sense that a backlash to the backlash is imminent. I can’t believe I had to watch that bullshit of an episode with my own two eyes #GameOfThrones pic.twitter.com/ue4hf0J18t— jedi in training (@totallyxtaylor) May 13, 2019 “I probably should’ve told someone the dragon lady was crazy.” #GameofThrones pic.twitter.com/YK3d6j5N27— Diane N. Sevenay (@Diane_7A) May 13, 2019 The carnage was insane and dramatic and very Game of Thrones, but did it make sense? Hmmmmm….. Even if Dany was pissed and wanted to destroy Cersei why wouldn’t she just go straight to the Red Keep instead of zig zagging destruction through the city IT MAKES NO SENSE #GameofThrones— Jenna Guillaume (@JennaGuillaume) May 13, 2019 missandei, in heaven looking at kings landing. #GameofThrones pic.twitter.com/mjBFEdbM0z— Justin Jay, Conclave Liasion 💚💙💛 (@_DubzyWubzy_) May 13, 2019 Game of Thrones season 8 episode 5: Everybody hurts Yep, Dany basically burned everything down and killed thousands of people. Not sure if King’s Landing as we knew it even exists any more. Next week is going to be extremely interesting. Meanwhile… So you all just going to act like you didn’t see this coming? Danys been whack from the start and you’re all fools if you didn’t think this was going to happen #GameofThrones pic.twitter.com/GMQdOKXPWf— clara maxwell (@claramaxwell99) May 13, 2019 Me trynna figure out did I really watch all them seasons for this #gameofthrones pic.twitter.com/XpZCTA0TuS— tingz (@_Inez__) May 13, 2019 HBO & the 3 fans that are actually enjoying this season of #GoT pic.twitter.com/VgxQbvNdcQ— VS (@valon_sej) May 13, 2019 everyone say THANK YOU LENA HEADEY for her phenomenal perfomance as cersei lannister, one of my favorites ever.power is power. you will be missed.#GameOfThrones pic.twitter.com/ycwauGBjFh— lucca (@davnerys) May 13, 2019 meanwhile tormund and ghost #GameOfThrones pic.twitter.com/x9WQH2tLDH— 💌 (@hugehoops) May 13, 2019 Game of Thrones
A drug that stops the spread of cancer has been developed, with scientists identifying the cells responsible for initiating and promoting metastasis. While the drug has only been tested on mouse models, researchers are hopeful the discovery will have widespread applications for future cancer treatments.Metastasis the process through which cancer spreads from one part of the body to another. It is one of the aspects of the disease that makes it so deadly – indeed, it is the reason behind 90% of human cancer deaths. The process by which cancer spreads is extremely complex. The cells that trigger metastasis are not known, so the development of therapies to prevent it is challenging.However, a team of researchers led by Gloria Pascual of the Institute for Research in Biomedicine (IRB Barcelona) has now found these cells, and shown how they can be used to stop the spread of cancer.In a study published in the journal Nature, the team found a specific protein – CD36 – in the membranes of tumour cells that are responsible for taking up fatty acids (a receptor). The team discovered CD36+ cells in samples of human oral carcinoma (oral cancer).When CD36 was absent from the tumours, they did not develop metastasis. When it was added, the tumours became metastatic.Researchers then looked at CD36 in mouse models of oral, melanoma and breast cancer. After treating them with antibodies to block the receptor, metastasis was either significantly reduced or totally eliminated. Furthermore, metastases already present shrunk or disappeared. Where matastases was already established, the treatment removed it in 20% of the cases, and reduced it in between 80-90% of the remainder. There were no significant side-effects observed.Cancer metastasis dependent on fat? Because CD36 is responsible for the uptake of fatty acids, the researchers looked at what role fat intake has on the spread of cancer. To do this, they provided one group of mice with a high-fat diet and inoculated them with oral cancer. In the control group, 30% went on to develop metastasis, compared to 80% of the high-fat group. This indicates a high-fat diet increases the risk of metastasis.Aznar Benitah said: In mice inoculated with human tumour cells, there appears to be a direct link between fat intake and an increase in metastatic potential through CD36. More studies are needed to unravel this intriguing relationship between diet and metastasis, above all because industrialised countries are registering an alarming increase in the consumption of saturated fats and sugar.Fat is necessary for the function of the body, but uncontrolled intake can have an effect on health, as already shown for some tumours such as colon cancer, and in metastasis, as we demonstrate here.Further analysis showed metastasis is also dependent on CD36 in ovarian, bladder and lung cancer. Findings indicate there could be a general mechanism that underlies metastasis – and treatments that block CD36 could be key to stop the spread of cancer.Although we have not yet tested this in all tumour types, we can state that CD36 is a general marker of metastatic cells, the first marker I know of that is generally specific to metastasis, said Salvador Aznar Benitah, head of the Stem Cell and Cancer Lab at IRB Barcelona.We expect this study to have a big impact on the scientific community and to further advances in metastasis research, and we hope to be able to validate the potential of CD36 as an anti-metastasis treatment. Things like this dont happen every day.The team is now working with researchers in the UK to develop antibody-based treatments that work against CD36 for a range of cancers. If successful, they believe a new drug could be available in five to 10 years. IBTimes VideoRelated VideosMore videos Play VideoPlayMute0:00/0:00Loaded: 0%0:00Progress: 0%Stream TypeLIVE0:00?Playback Rate1xChaptersChaptersDescriptionsdescriptions off, selectedSubtitlessubtitles settings, opens subtitles settings dialogsubtitles off, selectedAudio TrackFullscreenThis is a modal window.The media could not be loaded, either because the server or network failed or because the format is not supported.Beginning of dialog window. Escape will cancel and close the window.TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal DialogEnd of dialog window. COPY LINKAD Loading … Drug that stops the spread of cancer has been developed Close
To embed this piece of audio in your site, please use this code: Sid Hastings/APProtestors chant during the United Methodist Church’s special session of the general conference in St. Louis, Tuesday, Feb. 26, 2019. X Two Houston pastors interviewed by Houston Matters on Friday weighed in on the decision by the General Conference of the United Methodist Church to define marriage as the union of a man and a woman, and to add more punitive accountability measures regarding officiating same sex marriages. Additionally, LGBTQ+ individuals are still ineligible for ordination.The decision was reached at the meeting held in St. Louis this week by the church’s General Conference. After several hours of debate, the conservatives’ proposal, called the Traditional Plan, was approved by a vote of 438-384.John Stephens, senior pastor at Houston’s Chapelwood United Methodist Church, told Houston Matters that his congregation is very diverse and that when the U.S. Supreme Court legalized same sex marriage in 2015 the dialogue changed within the church.Stephens, who describes himself as a “centrist,” said he could accept that pastors officiate same sex weddings and he finds that the decision by the General Conference has hurt LGBTQ+ individuals. “What they hear in this is that: ‘I’m not loved, I can’t be a part of this church’,” he noted.Some members of the United Methodist church say that embracing practices that are friendly towards LGBTQ+ individuals would be allowing sin in the church, according to Stephens, who thinks the issue of homosexuality “is right at the forefront of our cultural angst.”“We live in a country where same sex marriage is legal. Now, as a church, we can build our walls higher and say who we want to let in or want to let out or not go out into the world and be in ministry. I just don’t, I fundamentally don’t agree with that. I don’t think that’s missional,” Stephens added.In a post published on his blog, the pastor said he thinks the conversation about changing the Methodist church to accept LGBTQ+ individuals will continue.Rev. Hannah Terry, of Westbury United Methodist Church and St. Mark’s Methodist Church, told Houston Matters Host Craig Cohen that people are “anxious” and feel hurt by the decision. She emphasized that she supports people in the church that are LGBTQ+ “all the way.”Terry said the Westbury congregation has a history of including all people, going back to the civil rights era when the congregation welcomed African American families into the church. “The general conference does not change that,” she said.“I am really concerned about the LGBTQ community,” Terry said, and added she is particularly concerned about “clergy that are queer and lay members that are queer.”After the meeting of the General Conference, Kenneth H. Carter, president of the Council of Bishops, said he is concerned the plan approved this week will cause progressive churches to leave the denomination.Asked about a potential formal split in Houston congregations from the denomination and the General Conference, Terry responded: “I don’t know.”With nearly 7 million members, the United Methodist church is the second largest Protestant denomination in the United States. Listen 00:00 /09:14 Share
Citation: Waiting periods reduce deaths from guns, study suggests (2017, October 17) retrieved 18 August 2019 from https://phys.org/news/2017-10-periods-deaths-guns.html Explore further (Phys.org)—A trio of researchers with Harvard Business School has found evidence that they claim shows gun deaths decline when states enact waiting period laws. In their paper published in Proceedings of the National Academy of Sciences, Michael Luca, Deepak Malhotra and Christopher Poliquin describe their study and discuss their results. More information: Michael Luca et al. Handgun waiting periods reduce gun deaths, Proceedings of the National Academy of Sciences (2017). DOI: 10.1073/pnas.1619896114AbstractHandgun waiting periods are laws that impose a delay between the initiation of a purchase and final acquisition of a firearm. We show that waiting periods, which create a “cooling off” period among buyers, significantly reduce the incidence of gun violence. We estimate the impact of waiting periods on gun deaths, exploiting all changes to state-level policies in the Unites States since 1970. We find that waiting periods reduce gun homicides by roughly 17%. We provide further support for the causal impact of waiting periods on homicides by exploiting a natural experiment resulting from a federal law in 1994 that imposed a temporary waiting period on a subset of states. Gun laws requiring domestic abusers to surrender firearms could save lives There is no debate regarding the numbers of people that are killed each year in the United States from bullet wounds—good records exist. The average is now up to 33,000 each year. What remains up for debate is what to do about it. Some individuals and groups have proposed enacting laws restricting gun sales, while others vehemently object to any such restrictions, citing their right to bear arms as spelled out in the Constitution. Somewhere in the middle, there are possible ways to reduce gun violence by enacting less restrictive laws. One such approach is to mandate that anyone buying a gun must wait a specified number of days after the purchase before taking possession of it. The idea is that a waiting period reduces murders and suicides because it gives those gun buyers time to cool off and think a little bit more about their plans before obtaining a gun. Unfortunately, evidence of whether this actually happens has been scant because the U.S. government has enacted laws disallowing the government from funding studies seeking answers to such questions. In this new effort, the researchers circumvented that problem by asking for and receiving funding directly through their own institution.The study consisted of two parts: The first looked at differences in gun death rates between states that had waiting periods and those that did not over the period between 1970 and 2014. The second part consisted of looking at changes in gun death rates in states that enacted waiting periods after passage of the Brady Handgun Violence Prevention Act in 1994, which essentially forced all states to enact waiting periods.Results from the first part of the study showed on average 17 percent fewer gun-related deaths for states with a waiting period (and approximately 10 percent fewer gun-related suicides). Results from the second part of the study nearly mirrored the first—the trio found that gun-related homicide deaths following passage of the Brady Bill dropped on average 17 percent while gun-related suicides dropped approximately 6 percent.The researchers suggest their findings indicate that if the U.S. were to implement a nationwide waiting period for gun purchases, the country as a whole could reduce annual gun deaths by approximately 1,700 a year. Journal information: Proceedings of the National Academy of Sciences © 2017 Phys.org Credit: CC0 Public Domain This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
Maharashtra has it all – from rich heritage sites to stunning beaches, wildlife sanctuaries to pretty hill stations. And of course Bollywood. To get the tourists to pick Maharashtra as their next destination, the Maharashtra Tourism Development Corporation (MTDC) held a road show in the Capital. Maharashtra has variety of spots to visit. The state is blessed with heritage sites like caves of Ajanta-Ellora, pilgrimage sites like Shirdi-Saibaba temple, hill stations like Mahabaleshwar- Panchgani and Matheran among others. Also Read – ‘Playing Jojo was emotionally exhausting’For nature lovers wildlife sanctuaries like Bhamragarh, Bor Dam, and Dajipur are a few must visit spots. Offering the perfect opportunity to be one with nature, these sanctuaries preserve the natural habitat of the protected animals. If you are the traditional holiday person, Maharashtra has its beautiful beaches. Places like Raigad, Harihareshwar, Bhandrapule and Kunkeshwar with their postcard perfect sceneries are the best places to relax far away from the mad rush of the city. Also Read – Leslie doing new comedy special with NetflixAdventure sport enthusiasts can set their sights on the amazing wild life sanctuaries, adventure trek spots like the Shayadri Mountains or rock climbing at Karla Mountains. And then there’s Mumbai, the heart of the state that encapsulates the power of economy, the glamour of Bollywood and the crazy diversity of the entire country in one city. If India had to pick one city to be the face of the country – Mumbai perhaps would be it. If spirituality interests you, the new Buddha circuit should be on your travel list. Made of seven inner circles and 25 recently discovered sites, some of them which 2200 years or older, the Buddha circuit is open for tourists now. ‘We have discovered new sites which are open for tourists; it will serve as spiritual break-through for the visitors,’ said Jagdish Patil, MD, MTDC.With the opening of its new tourist information center at Hotel Janpath, MTDC will now cater maximum people from north India. As the Torism Minister said – they have the foreign figures, the focus is on domestic ones now.Soon MTDC will unveil centers at Lucknow and Tirupati. The center was inaugurated by Maharashtra Tourism Minister Chagan Bhujbal. Patil also spoke about safe tourism for all, ‘We are taking several progressive steps to encourage tourism in Maharashtra; many interactive sessions with tour operators will take place to understand how we can get maximum tourists to our land. Also, we have tourism police everywhere, domestic and foreign tourists can be assured of safety and pleasant experience.’If you are planning to head out of the city this festive season – pick Maharashtra, you won’t be disappointed.
Kolkata: The Central Himalayan zone that covers North Bengal (Darjeeling Hills) and Sikkim, has the highest faunal diversity in the entire Himalayan region. Altogether, 14,183 species of animals have been found in this region, out of a total of 30,377 species in the entire Indian Himalayas, which comprises East, Central and West Himalayas.The findings have been documented in a book titled Faunal Diversity of Indian Himalayas, which is the fruit of a collaborative effort of about 85 taxonomic/biodiversity experts of Zoological Survey of India, under the guidance and leadership of its present director, Dr Kailash Chandra. The book was released on April 26 by C K Mishra, Secretary of Ministry of Forest and Climate Change at Dehradun. Also Read – Heavy rain hits traffic, flights”The total of 30,377 species of all the groups of animals that include protozoa to mammalia, represents around 30.16 percent of the total Indian fauna. None of the 10 biogeographic zones in the country, as per records, have so many fauna as these two zones,” said Dr Chandra.It may be mentioned that the entire Indian Himalayan region comprises of six states, which are Jammu and Kashmir, Himachal Pradesh, Uttarakhand, Arunachal Pradesh, North Bengal (Darjeeling) and Sikkim and two biogeographic zones – the Himalayas and Trans-Himalayas. These two biogeographic zones span across 12.03 percent of the total landmass of India. Also Read – Speeding Jaguar crashes into Merc, 2 B’deshi bystanders killedThe Himalayas extend 2,400 km in length across the country and covers an area of 3,95,485 square kilometers, including some parts of Pakistan, Nepal, Bhutan and China.As per findings, there are 280 species of mammals, 940 species of birds, 316 species of fishes, 200 species of reptiles and 80 species of amphibians known from Indian Himalayas. The region has 27.6 percent of the total vertebrate fauna of the country. There are 133 species that have been reported to be threatened as per IUCN criteria, 84 species have been categorised as vulnerable, 35 as endangered and 14 others critically endangered. The complete name of the species and the details of the exact province from where it has been reported, have been included in the book that has as many as 52 chapters. The study has gone on for over a century, and the compilation work had started two years back. Apart from Chandra himself, scientists Devanshu Gupta, K C Gopi, Basudev Tripathy and Vikas Kumar were also involved in the compilation work.”This book will be the baseline data for future works on the faunal study of the Indian Himalayas and also for the conservation and management of the entire biodiversity in the Indian Himalayan region,” Chandra said.The book discusses the threats and conservation strategies and tries to find out gap areas in research of the fragile ecosystems of Himalayas, which is subjected to rapid deforestation, habitat degradation and climate change.
Launching this winter: Vancouver-Yellowknife service with Air Canada Posted by Share Wednesday, July 26, 2017 Travelweek Group Tags: Air Canada, Canada, New Routes << Previous PostNext Post >> VANCOUVER — Air Canada will soon become the only carrier to offer daily service between Vancouver and Yellowknife.Starting Dec. 15 and running until April 1, 2018, the new service will launch with special introductory fares starting at $219 one-way, all in. Tickets are now available for purchase. Service will be onboard 75-seat Bombardier CRJ-705 aircraft featuring a choice of Business Class or Economy service, operated by Jazz Aviation under the Air Canada Express banner.“We continue to strategically build our Vancouver hub and we are excited to link Vancouver and Yellowknife with daily non-stop flights this winter, complementing our existing Yellowknife services from Calgary and Edmonton. These new non-stop flights will shave off almost four hours of round-trip travel time for customers travelling between Canada’s west coast and the Northwest Territories. In addition to convenient business travel between these two areas, these new flights also connect seamlessly at our YVR trans-Pacific hub to and from our Asia and US transborder networks, offering one-stop ease for visitors travelling to enjoy Canada’s spectacular Aurora Borealis and northern winter adventures,” said Benjamin Smith, President, Passenger Airlines, at Air Canada.More news: Direct Travel names Smith as Senior VP, Leisure Marketing, North AmericaWally Schumann, Minister responsible for the Department of Industry, Tourism and Investment, and the Department of Infrastructure, in the Northwest Territories added: “Air Canada’s direct route between Yellowknife and Vancouver is great news for the Northwest Territories’ tourism industry and comes just in time for aurora-viewing season. The additional flight enables our visitor numbers to continue to grow by providing travelers with easier and faster routes so they can spend more time enjoying the spectacular Northwest Territories, and comes at a time when the Yellowknife airport is actively working to attract more business and enhance services to clients and passengers.”So far in 2017, Air Canada has launched new services from its Vancouver hub to: Taipei, Frankfurt, London-Gatwick, Dallas-Fort Worth, Denver, Boston, with Melbourne seasonal flights to begin December 1, and Delhi seasonal service resuming on October 14 increasing up to five times weekly for the 2017/2018 season.