IPL 2019 Sunrisers Hyderabad preview and SWOT analysis Will Kane chokeslam the

first_img File photo of Sunrisers Hyderabad captain Kane Williamson.IANSThe leadership group at SRH is perhaps the strongest and at its helm is one of the most astute minds in world cricket — Kane Williamson. The backroom staff of SRH is fantastic and they are like a family who does not put unnecessary pressure on the players. The like of Tom Moody, VVS Laxman and Muthiah Muralitharan are more like catalysts and enablers that help the players play their natural game by expressing their own skills in the ways they know best. Weaknesses The batting form of Manish Pandey has not been great and David Warner is returning after a long layoff. Thus, the pressure of run scoring will fall heavily on the shoulders of Williamson. The team has a decent middle-order but none of them can be ascertained as match-winners. Yusuf Pathan is a difference maker on his day but he is towards the end of his career. Read: Predicted playing XIsOpportunities SRH has the perfect opportunity to lift another title. They have one of the most balanced teams heading into the tournament and like they always do, they purchased very shrewdly in the auction this time too. The likes of Rashid Khan, David Warner, Bhuvi and Williamson are all big match players who can turn games on their own. Thus, another strong season is expected in Hyderabad. This IPL will provide Warner with the perfect opportunity to get back to a high standard of cricket. Following his ban, the left-hander has played club level cricket which is a far cry from international standards. Thus, he will see the IPL as an opportunity to get back into shape for the upcoming World Cup. Threats SRH has a lot of players who perform a similar role which gives the management a headache in terms of keeping the entire camp motivated and happy. Shakib Al-Hasan and Mohammad Nabi have similar jobs; the five pacers will not get a game every time; Jonny Bairstow, Wriddhiman Saha and Sreevats Goswami will be vying for the same role. Even Yusuf Pathan and Deepak Hooda are similar types of players.  IBTimes VideoRelated VideosMore videos Play VideoPauseMute0:05/1:19Loaded: 0%0:05Progress: 0%Stream TypeLIVE-1:14?Playback Rate1xChaptersChaptersDescriptionsdescriptions off, selectedSubtitlessubtitles settings, opens subtitles settings dialogsubtitles off, selectedAudio Trackdefault, selectedFullscreenThis is a modal window.Beginning of dialog window. Escape will cancel and close the window.TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal DialogEnd of dialog window. COPY LINKAD Loading … Squad Kane Williamson (C), Basil Thampi, Bhuvneshwar Kumar, Deepak Hooda, Manish Pandey, Natarajan, Ricky Bhui, Sandeep Sharma, Shreevats Goswami (WK), Siddarth Kaul, Syed Khaleel Ahmed, Yusuf Pathan, Billy Stanlake, David Warner, Mohammad Nabi, Rashid Khan, and Shakib Al-Hasan, Vijay Shankar, Shahbaz Nadeem, Abhishek Sharma, Wriddhiman Saha, Jonny Bairstow, Martin Guptill Close One would not ideally fancy Sunrisers Hyderabad to be tough competitors in the Indian Premier League but it is a team everyone likes. They are every opposition fan’s second favourite team but within the camp, they have been able to foster an atmosphere of success. SRH finished runners up last season despite their campaign tailing off slightly after a bright start. This season, they have bid goodbye to Shikhar Dhawan but will welcome David Warner back to the fold. The franchise has also acquired the services of Vijay Shankar who came their way in a trade which involved Dhawan going to the country and tournament’s Capital. Here’s taking a look at SRH’s strengths, weaknesses, opportunities and threats.Strengths The team is filled with quality Indian seam bowling options in Bhuvneshwar Kumar, Siddharth Kaul, Sandeep Sharma, Basil Thampi and Khaleel Ahmed. This gives them the opportunity to stack their batting and all-rounders with overseas players. In Bhuvi and Kaul, they have quality death bowlers too. The plethora of options also allows the captain to pick and choose depending on the conditions while keeping everyone fresh.  Sunrisers Hyderabad to take on Chennai Super Kings in IPL 2018 finals Tom Moody has impressed with the Sunrisers Hyderabad in the IPLIANSIf the mystery of Rashid Khan is decoded, the bowling attack suddenly looks much less threatening. In the age of technology, it may so happen that the opposition does figure him out and that remains a constant threat.  last_img read more

Driver helper confess to raping girl in running truck

first_imgA truck driver and his helper reportedly confessed before separate courts here on Sunday to raping a teenage girl in their running vehicle.Senior judicial magistrate Akhtaruzzaman recorded the statement of driver Mehedi Hasan while senior judicial magistrate Aftabuzzaman that of helper Sohan alias Tuhin under section 164.Later, they were sent to jail, said court police inspector Sohel Alam.Earlier on Thursday, a court placed the duo on a four-day remand in a case with Siddhirganj police station over the rape of the girl in the running truck.Police said Mehedi and Sohan picked up the 15-year-old girl, who left her house following a brawl with her mother, from Chourasta in Gazipur city around 8:00pm while she was standing there alone promising that they would reach her home.However, the duo raped the girl in the running truck throughout the night threatening to throw her to death from the truck. As the truck stopped in front of the main gate of ACI Pharmaceuticals at Panirkall in Siddhirganj upazila on Wednesday morning, the victim started screaming from inside the truck.Later, locals rushed in and rescued her. However, the driver and helper managed to flee the scene.Later, police arrested Mehedi from in front of Adamjee Sonamia Market in Siddhirganj on Wednesday while Sohan from Godanail of the upazila on Thursday morning.last_img read more

A biography in montage

first_imgArab filmmaker Rania Stephan’s first feature film that sheds light on the life of Egyptian star  Soad hosni will be screened in the Capital this month. The Three Disappearances of Soad Hosni is Rania Stephan’s attempt to tell the story of Soad Hosni, one of Egypt’s most famous film stars who starred in eighty-two feature films between 1959 and 1991. Stephan’ first feature film will be showcased in the capital from 3 to 18 August in the Capital.  Using the technique of filmic montage, Rania Stephan creates a moving portrait of the iconic actress, in which the rumours surrounding her life and death are translated through her image as a projection of the Arab imaginary and its evolution over thirty years. Soad Hosni had fallen from a building on London’s Edgeware Road in 2001. Also Read – ‘Playing Jojo was emotionally exhausting’The film was awarded a Sharjah Biennial Prize in 2011. According to Stefan, ‘The entire film is made from images and sound taken from Hosni’s films. It is built like a tragedy in three acts that ends in death. The film operates like a kind of pre-vision on the tragic destiny of this actress’.Stephan’s film is also a celebration of popular Egyptian cinema, historically sidelined by both Arab critics and the West. ‘I wanted to give popular culture its credence, its value’, says Stephan. Also Read – Leslie doing new comedy special with NetflixBorn in Beirut – Lebanon, Rania Stephan graduated with a degree in Cinema Studies from Latrobe University in Melbourne, Australia and a graduate degree in Cinema Studies from Paris VIII University, France. Her career in film production has been long and diverse. She has worked as a sound engineer, camera person, editor and first assistant with renowned filmmakers including Simone Bitton (Rachel, Wall, Citizen Bishara) and Elia Suleiman (Divine Intervention). Her work ranges from creative videos to raw documentaries. The Three Disappearances of Soad Hosni is her first feature film. For film buffs, this is a perfect fortnight long opportunity to witness Stephan’s work right here in the Capital. Mark your calendars.last_img read more

Superhero posters can trigger people to help others

first_imgLooking at posters of superheroes can trigger prosocial behaviours in people, encouraging them to lend a helping hand to others, a study has found. Superhero movies set inspirational moral examples for many people, but whether they encourage people to help a stranger or donate money is not known. “Given that superheroes are an increasingly large and accessible part of our cultures, even if merely symbolically, we were interested in exploring their role in inspiring virtuous and meaningful lives,” said Jeffrey D Green of the Virginia Commonwealth University in the US. Also Read – Add new books to your shelf”We decided to study the effect of well-known fictional heroes, such as Superman or Spiderman, as people may tend to be more motivated to emulate behaviours where there is little realism,” said Green. The researchers exposed 245 individuals to common household pictures with either subtle superhero images – such as Spiderman and Superman – or neutral images. Participants primed with superhero images reported greater intentions to engage in prosocial behaviours. The perception of meaning in life was not directly influenced by the superhero prime, but indirectly through helping intentions: the superhero prime increased helping intentions, which, in turn, increased felt meaning in life. Given that the experiment relied on self-reported helping intentions, a second experiment was performed to examine actual helping behaviour. Also Read – Over 2 hours screen time daily will make your kids impulsiveA further 123 individuals were subtlety primed with a superhero image versus a neutral image, then invited to help with a tedious experimental task for no extra credit. Those primed with the Superman poster were significantly more likely to help than those primed with a bicycle. “These experiments highlight how even the subtle activation of heroic constructs through visual images of superheroes may influence intentions to help as well as actual helping behaviour,” said Green. Future research could advance this work by examining the effects of real-life heroic figures, who may or may not be known personally, which also adds the element of possibly flawed characters.PTIlast_img read more

Localised versions of majority Dreamworksowned mu

first_imgLocalised versions of majority Dreamworks-owned multichannel network Awesomeness TV has officially launched in the UK, Spain, France, Germany and Brazil.The launches, done in partnership with Endemol Shine Group, follow an initial rollout of the MCN in the UK last month, with local language versions and original content now available in each of the five new countries.“We are extremely proud of our alliance with AwesomenessTV and are thrilled to be launching simultaneously in five countries. Using our creative talents across the group we have got some really exciting formats which going forwards we will be able to roll out worldwide,” said Wim Ponnet, group director of commercial and strategy, Endemol Shine Group.Kelly Day, chief digital officer, AwesomenessTV, added: “With this launch we are able to extend the reach of AwesomenessTV to fans who can now enjoy our programming in their own language.“Localised versions of the AwesomenessTV formats are working incredibly well, proving Gen Z content knows no boundaries. The creation of great original content delivers on our promise of providing new opportunities and resources for local talent.”Endemol Shine Group signed a strategic alliance with the MCN to extend the international reach of the AwesomenessTV brand at MIPCOM in October.AwesomenessTV aims to engage the global ‘Generation Z’ audience through original content on multiple platforms – including YouTube, mobile, OTT, social media, film and television.The MCN is owned by DreamWorks Animation and Hearst, with the latter holding a 25% interest.last_img read more

UKbased pay TV broadcaster Sky has acquired Diago

first_imgUK-based pay TV broadcaster Sky has acquired Diagonal View, the digital channels company behind the All Time 10s and Football Daily online brands.Sky has been in acquisitive mode in 2017, buying stakes in True North and Chrysalis Vision, and has now taken over nine-year-old Diagonal View.Sky sees the acquisition as broadening its engagement with young, digital-first audiences who may not be taking pay TV services, and as a way of offering “greater brand-safe digital opportunities to advertisers”.Diagonal View is best know for its All Time 10s channels, which use social videos to run content on a diverse range of content that spans The Fresh Prince of Bel Air to unexplained phenomena. It has more than 15 million subscribers, with more than one billion in the past year.Diagonal View’s existing management team, including co-founder Matt Heiman, will continue to lad the business from within Sky, whose group director of advanced advertising Jamie West and director of digital sports and news David Gibbs will now support the unit.“Our social channels complement Sky’s current portfolio – the prospect of our incredibly popular Football Daily channels collaborating with Sky, whose pedigree in this space is unrivalled, is extremely exciting,” said Heiman.“Sky brings rights, expertise and scale. Diagonal View knows how to make content that digital natives enjoy watching and engaging with, so this partnership feels like a natural win-win for both us and Sky.”On the digital side, Sky invested in digital rights management firm TRX in August last year, and has heavily invested in Asian SVOD service iFlix.last_img read more

Spanish regional cable operator Euskaltel has outl

first_imgSpanish regional cable operator Euskaltel has outlined plans to grow its revenue to €800 million, with EBITDA of €400 million, by 2022, with its expansion into new markets accounting for 8% of revenues by that date.The ambitious turnover target would imply growth of 28.6% on the company’s figure for 2017, with the EBITDA figure 30.3% up on the 2017 number.Francisco ArtecheUnveiling the targets at an investors day presentation in Madrid, Euskaltel management said an EBITDA margin of 30% of sales would be sustainable by 2022, enabling double-digit growth in dividends across the timespan of its strategic plan. The company predicts that net financial debt will fall below 3.5x EBITDA by 2022.Euskaltel has appointed Charo Lacal to head up a recently created operations and transformation division bringing together customer service and management into a single unit. Lacal will be tasked with ensuring that the group’s different functional areas adapt to new market scenarios.CEO Francisco Arteche said that the group would focus on improving customer experience, a return to growth in the B2B segment, digital transformation, strategic alliances and an increased reach.Euskaltel has also identified cost savings of €40-45 million as it streamlines its operations and increases efficiency.“Thanks to its management capacity, the Group estimates a very significant increase in revenues in the markets we are expanding into over the next few years, reaching 8% of total revenues by the end of 2022,” said Arteche.Euskaltel’s presentation comes as 15% shareholder Zegona Communications completes a capital increase to finance the acquisition of Euskaltel shares.Zegona – the former owner of Asturias operator Telecable that was acquired by Euskaltel – has said it wants to see Euskaltel expand its reach within its core markets of the Basque Country, Asturias and Galicia as well as extending its reach to other regional markets. The company has been in talks with former Jazztel CEO José Miguel García, who participated in its placing, about taking a role with the company and also wants to facilitate a deal to bring the Virgin brand to Spain as a vehicle for Euskaltel’s national expansion.Zegona has identified a similar level of cost savings to that outlined by Euskaltel’s management through the creation of a single operating platform for the group’s three reginal brands and other measures.last_img read more

This year has seen a rapid expansion of Discovery

first_imgThis year has seen a rapid expansion of Discovery’s footprint internationally under president and CEO Mark Hollinger, following the group’s decision to split its European business into a western European division under Dee Forbes and CEEMEA under Kasia Kieli. The female-skewed TLC channel recently passed 100 million homes, following launches in Denmark, Finland and Poland.Age 52Education J.D. from Yale Law School and a B.A. degree (summa cum laude) in history and political science from Colgate University.Previous positions Paul, Weiss, Rifkind, Wharton & Garrison, senior associate, 1985-91; Columbia Law School, lecturer, entertainment law, 1988-91; Discovery Communications, VP/deputy general counsel, 1991-94; Discovery Channel Asia, acting GM, ‘94 ; Discovery Communications, VP international business development/ VP, deputy counsel, 1995-96; general counsel, 1996-2001; EVP, corporate operations, 2001-03; senior EVP, corporate operations/general counsel, 2003-07; COO, 2008-09Last year’s highlights The successful rollout of TLC; industry-leading results.Last year’s most significant development The continued momentum toward a VOD world – whether Netflix, UPC’s Horizon initiative, iPlayer or TV Everywhere.Goals for next year Continue to build the strongest non-fiction portfolio in global pay television.Industry challenges and opportunities Figuring out the business model for programmes in the VOD environment in order to continue investments in great content; and figuring out how the VOD environment can co-exist successfully with the traditional pay TV environment.Alternative career choice Sports management – as with TV, it would give me a chance to work every day with something I love.TV character most identified with A contestant on The Amazing Race – always on the go, with lots of challenges to faceMost admired personality Jimmy Carter, who has used his position to promote important, but unglamorous, causes like free elections and affordable housing.Life outside work Hang out with my three sons, watch football, read and, crazily enough, travel.last_img read more

John Why are some of the phishing scams so blatan

first_img John: Why are some of the phishing scams so blatantly stupid? Like a Craigslist price of $2,307 for a 2013 BMW. It’s obvious to anyone. Durk: “Oh gee, I’m a Nigerian prince and I want to move $50 million to America and I’ll give you half of it if you help me.” Why are people trying a scam that’s so stupidly obvious? The answer is very simple: These are competent and professional fraudsters. If somebody falls for the Nigerian prince thing, then they’ll be stupid enough to give the fraudsters their Social Security number, their bank account number, and their password. With the Nigerian prince scam, the fraudsters get rid of the 99% of the people that aren’t that stupid right away. John: Ah. The more inane the fraud pitch is, the better the fraudsters target their market to the stupid. Doug, what’s your definition of stupidity again? Doug: Stupidity, like intelligence, comes in a number of flavors. The most common definition of stupidity is “of low intelligence” – but that’s rather circular, like saying “slow” means “not very fast.” I like to define “stupid” as the ability to see the immediate and direct consequences of actions, but the inability to see the delayed and indirect consequences. Like most criminals, black-hat hackers never see the long-term consequences – like being hunted, being held in contempt by most of society, and probably landing in jail. Or indirect consequences – like destroying their self-respect. Among other things. An even better definition of stupidity, applicable both to those who respond to the Nigerian prince scam as well as the Nigerian Prince himself, is “an unwitting tendency towards self-destruction.” Even when criminals score high on IQ tests, they still fit this definition. So while computer criminals are undoubtedly smarter than street criminals, they’re still rather stupid in very important ways. Durk: It’s relatively easy to protect yourself from being financially harmed in a hack. The first rule here is, don’t let a million different companies have your credit card number. Almost every company is perfectly willing to deal with a debit card rather than a credit card. If you keep a small amount of spending money in a debit card account, then that’s the most you can lose. And if it’s not your fault, you’re probably going to be made good. Second, you use encrypted wire transfers with your bank to make deposits. You see that little padlock up on the address line on your browser that says https rather than http? That’s an encrypted link. Just make sure that you or your browser entered your bank’s internet URL. Don’t click on an email link that appears to have come from your bank, because it may be a fraudulent phishing email that takes you to a URL with an https connection and a padlock that is NOT really your bank but sure looks exactly like your bank’s internet page and likely will have a confusingly similar URL! Recommended Link The next step is to keep your attack surface to a minimum. An attack surface is the path that you could be attacked through. For example, the more companies that have your credit or debit card numbers, the bigger your attack surface. When you buy something on the phone, tell them, “I don’t want my credit card number or debit card number being kept permanently on file. I just want to do this one transaction with you and don’t want to set up an account.” It’s in their computer and memory just long enough to clear with the bank or the credit card and then it’s gone. If the company then gets hacked, you are safer. There are only two places that have my debit card number permanently on file: PayPal and Amazon. Both of those are really serious about security. John: But the bad guys can be mighty sneaky. Durk: Yes. Clicking on an ad can load malware onto your computer if you’re not careful, especially if you use Windows. With a Mac, Gatekeeper will ask for your password, warn you that you are about to load an un-vetted program, and ask if you really want to do this. Some of those ads are little more than a pixel in size. Companies that are selling ad space on their websites don’t do anywhere near what I think is adequate to check out the advertisers. If you use Adblock Plus with Firefox, you are protected because you will never even see the ad, let alone be able to click on it.Also, you want a more secure browser than something that’s provided by Microsoft or Google. They’ve got a file on you that’s bigger than the FBI, NSA, and the CIA put together. Every time you do a search they’ve got your IP address – that is your internet protocol address which identifies you uniquely – and they also have years and years of tracking every search you’ve ever done, what you search for, and what you clicked on after you did the search. That is a vast amount of information. With that information and a bit of computer intelligence, they can figure out that your daughter is pregnant before you know it yourself. Deciphering masses of disparate data to allow for conclusions results from the availability of these dense patterns of information, in what is called the matrix effect. Microsoft and Google both make more money off of your personal information than they make off any products. The last time I looked at the contract for Windows 10 for individual users, it was 140 pages long. Buried inside there’s a section that essentially says, “All information on your computer belongs to us and we can do anything with it we want.” You agree to this by checking a box that you never read. Any time you do a Google search they’re harvesting information from you. They’ll sell it to anybody. They’ll sell it to the FSB/KGB, the DEA; they’ll sell it to the cops. If you’re getting a service for free on the internet, you need to know that you are the product. John: And they can sell this information to burglars who are local to you? Durk: Not intentionally, but yes, and these burglars then know what you drive, where you drive to and when, where your home is located. They know you’re asleep at 3 a.m., they know you have a Ferrari, they steal your Ferrari out of your driveway. John: How do you avoid this? Durk: In the case of Windows, there’s a free program you can get called ShutUp10. It reduces the amount of information getting delivered back to Microsoft from your computer. You need to keep that ShutUp10 up to date because Microsoft keeps changing the spyware they put on your computer. It’s a constant race. The web has turned into a massive theft of personal information used for marketing purposes. Also, when doing searches, go to – a ridiculous name, I know – DuckDuckGo.com. They’ll forward your search to Google and Bing and a whole bunch of other search engines, but they won’t forward your IP address, and they won’t keep a dossier on you and all your searches. Oh, incidentally, don’t use Facebook. Don’t use Twitter. They make all their money by selling your personal information. Just don’t use them. John: My son told me that travel booking sites substantially raise the available rates for flights if they see you shopping around for a specific trip. Indeed, it happened to me two days ago. I searched a fare three times during the day. The third time, the fare jumped up threefold and stayed high from then on. I thought I had missed out on a good fare. My son told me to try browsing incognito. Google Chrome has an incognito mode: turns it on. I turned it on, searched the flight again, and the price for my flight was the nice low one that it had quoted me initially. Sneaky. But I wonder if I can trust Google Chrome’s incognito mode for long. Durk: Google Chrome will still fink you out. I use Firefox, which has an incognito mode, with the extensions NoScript, Privacy Badger, Adblock Plus, Cookie Controller, and Random Agent Spoofer. Note that you do not have to restrict yourself to one browser when price shopping for expensive items. Justin’s note: Chris Wood, our tech expert and editor of Extraordinary Technology, recommended a cybersecurity stock last year that handed his readers triple-digit gains in little over a year. And he’s just found the company set to displace last year’s winner… for potential 130% profits. You can access the name of this company—and all of Chris’ latest research—with a risk-free trial subscription to Extraordinary Technology. Click here to learn more.Also be sure to check out Part 2 of Doug’s interview tomorrow, where the guys discuss other ways to start protecting yourself from hackers. Reader Mailbag Today, readers respond to our recent Dispatch on the future of electric-car maker Tesla… It’s the first time I have put pen to paper to you but I just have to say that I can’t agree more regarding your prognosis on Tesla. Believing what you have just said, back in March I placed a put, for June, on Tesla crashing, only to lose my $5,000 bet. Clearly the man [Tesla founder Elon Musk] is a perfect artist in front of the American investing public, who just follow and follow his dreams. I’m afraid that you are right, however. On the other hand, it’s great to see how you Americans can follow a dream. Is that not what makes America great? –Rodney Justin’s note: Over the next two days, I’m sharing a special interview that features Doug Casey and his colleagues on the latest crime wave that’s sweeping the globe.Below, you’ll hear from John Hunt, an MD and coauthor with Doug of Speculator and Drug Lord, and Durk Pearson, bestselling author and former rocket scientist and aerospace physicist. They recently sat down with Doug to share their best tips on how to protect yourself against the growing cyber-threat.I think you’ll find their ideas interesting and timely…John: Equifax hacks, Russian hacks, and political hacks are all competing with the Kardashians for primetime news reports. Let’s focus on something that might actually matter to each of us and that we can do something about: our own personal cybersecurity. Durk: Computer security is a lot more important than most people realize. Absent precautions, it’s like if you had a stack of $100 bills and left it on the sidewalk in front of your house. If someone happens to stroll through your neighborhood, he can just pick them up. Likewise, most people have no computer defenses at all. You have more than $100 bills in that computer. You have your future money too, and your credit. But you can become resistant to this. It’s not an impossible task. Remember the old story? You don’t have to run faster than the bear. You just have to run faster than the other guy. And that is surprisingly simple. John: So what do you advise that everyone should do now? Durk: First know that if you live in a gated residential community, you have a very low chance of being robbed. But the internet is as if everyone lives in Watts in the 1960s, or South Chicago now. John: You have to build your gates and walls. Durk: Right. Now, you don’t have to be a perfectly hard target. There is no such thing as a perfectly hard target. The CIA got hacked for a lot of their extremely dangerous hacking tools which are now out in the public domain. If the CIA can get hacked, believe me you can get hacked too. On the other hand, all you have to do is make yourself a much harder target than the value of what people can get out of you and you’re going to be left alone. They’re going to move on to somebody else who isn’t as tough. Which is most everybody. — This may spill over to SpaceX… Boring General Motors (GM) is safer. –Bruce — All Signs Point to a Giant Bull Supercycle In This Sector and the Masses Are Completely Ignoring It… Right now, the masses of “herd” investors are piling into mainstream stocks, completely convinced that this overvalued bull market will just “keep going.” But they’re ignoring an even more lucrative opportunity in a hidden sector completely outside of the equities market. Only a handful of millionaire “lone-wolf” contrarian investors are paying attention to it – licking their lips in anticipation of windfall profits that haven’t been seen in seven years. If you’re an independent thinker who is brave enough not to be just another “herd” investor, click here to learn the details of this “lone-wolf” opportunity. Recommended Link Do You Want to Profit From Today’s Marijuana Boom… But Not Sure Which Stocks to Buy? The marijuana market is on fire. Everyone wants to get rich with pot stocks today. With crazy gains of 7,820%… 17,300%… and even 69,000%, pot stocks like these averaged peak gains of 29,000%. But other pot stocks have tanked. Do you want to make money from today’s marijuana mania? Not sure which pot stocks are safe and which are risky? Then watch this presentation right now and see the 3 pot stocks to buy right now. It is interesting another guy is saying go long on Tesla and that it will be up in the high 300s by the end of Q4!–Williamlast_img read more

While Americans are busy dissecting the Michelle W

first_imgWhile Americans are busy dissecting the Michelle Wolf monologue at the White House Correspondents’ dinner, Nigerians (and experts on Nigeria) are busy expressing themselves about Monday’s meeting with President Trump and their president Muhammadu Buhari. It’s the first time Trump has met with a sub-Saharan African leader.Here’s a roundup of responses, from interviews with Nigerians and other commenters and from Twitter.Some are glad the meeting took place.”I am really excited about the recent developments, and I believe it’s a way of strengthening relationship between both countries,” says writer Divine Nwoye.Others are not fans of the U.S. President, especially in light of his reported use of a vulgar term to characterize African nations in January 2018.Desmond Okon, political commentator and resident of Lagos: “He’s a controversial human being who has a reputation for offensive comments. [Our] President should be careful with the things he says to avoid selling the country out.”Some praise Trump’s sympathy for the “killings of Christians”…Osita Obeta, who just joined he National Youth Service Scheme for the one-year mandatory stint: “I’ve always loved Trump and his frankness when it comes to talking about issues, and his stance on the senseless killings in Nigeria is a good one. Leaders should not shy away from calling a spade a spade.”… but others are skeptical.Some wonder why Trump only mentioned one group that’s suffering.And some are wondering about visas to immigrate to the U.S.There’s a call for action, not just talk.Victor Ejechi, a recent graduate of the University of Benin who lives in Lagos: Trump’s remarks needs to be acted upon before we can have a full-blown celebration. Rhetoric statements on fighting human trafficking, corruption and insecurity don’t solve problems. I hope Buhari returns to Nigeria energized to take serious actions on what he discussed with Trump.”They’re glad that corruption was mentioned but aren’t certain change is coming.Ejechi says Buhari’s war against corruption has not produced “good results”: “What have we done with all the recovered money? Has anybody been jailed for corruption?”Obeta has a different perspective: “Buhari has partly tried to eliminate corruption, but the people he is working with have not made it easy for him.”They’re glad that trade was brought up:Merit Ayibe, a journalism student: “I am happy they discussed trade because Nigeria needs to attract more investment rather than aid for real development to happen.”They have mixed feeling about U.S. aid.Ayibe: “No country can develop by depending on aid. Most of the aid we’ve collected in the past were not used well, in fact they could provide basic facilities that would address issues like malaria.”Okon: “Aid is good, but the question is what is the catch? What is the motivation behind it? If the agreement is safe after all considerations then I don’t have issues with it.”They speculate about why the meeting was held in the first place.Matthew T. Page, former State Department official and associate fellow at Chatham House: “Left to his own devices, I think President Trump would have minimal interest in meeting with President Muhammadu Buhari or any other African leader. This meeting is most likely the result of efforts by diplomats and other policymakers from both countries to bring together these two leaders to reaffirm the close — if not occasionally challenging — relationship between the United States and Africa’s largest economy and most populous country. The meeting offers presidents Buhari and Trump — both of whom are politically polarizing figures in their respective countries — the opportunity to appear engaged, statesmanlike and in control.”And everybody’s having fun with a photo of Buhari signing the White House registry:Linus Unah is a freelance journalist covering global health, conflict, agriculture, and technology in Nigeria. Find him @linusunah. Copyright 2018 NPR. To see more, visit http://www.npr.org/.last_img read more

Finding love is not easyBut Supreme Court Justice

first_imgFinding love is not easy.But Supreme Court Justice Ruth Bader Ginsburg counts herself among the lucky ones.She had an epic marriage to her late husband, Marty Ginsburg, that has been detailed in many places (here, here and here), including the RBG documentary.But this past year tested Ginsburg in a new way without the love of her life. She was diagnosed with cancer for the third time in 20 years late last year, and it was the first time she has had to wage the fight without Marty.”My first two cancer bouts — both colorectal cancer at Washington Hospital Center and pancreatic cancer at Sloan Kettering — Marty stayed with me,” Ginsburg told NPR’s Nina Totenberg in an interview on July 23. “He stayed with me in the hospital sleeping on an uncomfortable couch despite his bad back. And I knew that someone was there who really cared about me and would make sure that things didn’t go wrong.”Don’t see the video? Click here.Throughout his life, Marty, who was one of the preeminent tax lawyers in the country, was a principal booster of his wife. He played a behind-the-scenes lobbying role, for example, in her eventual appointment to the Supreme Court. He was even the principal cook for his wife and children in an era when most men took a back seat on domestic duties, and no one seemed to relish Ruth’s accomplishments more than Marty.And he was always looking out for her, like that one time in the hospital when, without him there, Justice Ginsburg might have died.”There was one day during [the] colon cancer bout when I was getting a blood transfusion, and Marty saw that something was very wrong,” Ginsburg said, “and he immediately yanked the needle out of me. It turned out that there was a mismatch not in the type of blood but in some antigen. I might not have lived it if he hadn’t been there.”He encouraged her to go to a physical therapist. That famous exercise regimen of hers might not have happened were it not for Marty.”I didn’t want to do it,” Ginsburg said. “I was exhausted, and Marty said, ‘You do it.’ And he was quite insistent about that. So, to have his loving care and yet his determination that I do what was necessary to heal faster, it was hard to be alone.”When she was recovering from cancer twice before, Marty would cook for her, walk with her, read to her and make her laugh.”Marty had a wonderful sense of humor, as you know,” Ginsburg said.Ginsburg is reminded of Marty every day, especially, she said, when the newspaper arrives.”He was my clipping service with The New York Times and The [Washington] Post,” she said. “I miss him every morning, because I have no one to go through the paper and pick out what I should read.”Now with him gone, Justice Ginsburg cherishes Marty’s memory. But, to get by, she has dived into her work at the court. “The work is really what saved me,” she said, “because I had to concentrate on reading the brief doing a draft of an opinion, and I knew that had to get done. So I had to get past whatever my aches and pains were. Just do the job.” Copyright 2019 NPR. To see more, visit https://www.npr.org.last_img read more

Disabled activists say governmentfunded research

first_imgDisabled activists say government-funded research, which concludes that the programme to reassess people on incapacity benefit through the work capability assessment (WCA) was linked to 590 suicides in just three years, is both “damning” and “timely”.Campaigners, doctors and psychiatrists have been warning for several years of strong anecdotal evidence that the programme to reassess hundreds of thousands of old-style incapacity benefit (IB) claimants was causing significant harm and distress, particularly to people with mental health conditions.But now public health experts from the Universities of Liverpool and Oxford have shown in a study that, for every 10,000 IB claimants who were reassessed in England between 2010 and 2013, there were an additional six suicides, 2,700 cases of self-reported mental health problems, and an increase of more than 7,000 in the number of anti-depressants prescribed.The most significant increases took place in the most deprived local authority areas of England.Across England as a whole, the reassessment process from 2010 to 2013 was “associated with” an extra 590 suicides, 279,000 additional cases of self-reported mental health problems, and the prescribing of a further 725,000 anti-depressants.The idea for the research came originally from disabled activist Rick Burgess (pictured), who later co-founded the grassroots campaign group New Approach, and wanted “recognised and respected epidemiologists” to carry out “an academically-rigorous study” into the number of deaths caused by the WCA, with the results to be reported before the 2015 election.Together with three other leading campaigners – artist-activist Liz Crow* and New Approach co-founders Jane Bence and Nick Dilworth – Burgess began discussing the idea early last year with David Stuckler, professor of political economy and sociology at Oxford and one of the new study’s co-authors.Stuckler concluded at the time that such research was not possible because the necessary data had not been released by the government.Burgess pointed out that the research had been “started by disabled people with no funding”, but he said it was “brilliant” it had been completed, and that he felt “grimly vindicated” by evidence which would, “in any functioning democracy”, cause a government to be removed by a vote of no confidence.He said: “It does show welfare reform is causing excess deaths, which is what we have always said, and it has been reported in most media, so the idea to have a rigorous, reputable study done was worth it for campaigners, even though it is not exhaustive and there is much data still to be wrestled out of the hands of this very secretive government.”Linda Burnip, co-founder of Disabled People Against Cuts (DPAC), said: “This research simply confirms what we’ve all known for a long time, but is very timely both in relation to the ongoing UN inquiry into the grave and systematic violation of disabled people’s human rights and to DPAC’s campaigning priorities for 2016.“The main focus of this campaigning will be an end to people being wrongly pushed to their deaths by the current benefit system inflicted on them by [work and pensions secretary] Iain Duncan Smith.”Mark Harrison, chief executive of Equal Lives, said the research was “very timely and damning of a brutal system which is damaging people’s mental health”. He said it was clear the government was intent on cutting public spending and dismantling public services “whatever the human consequences”. He said: “To them, people who commit suicide or whose mental health conditions deteriorate as a result of their policies are merely collateral damage in their austerity war. “I am sure the government will ignore the evidence in this report as it does with all the facts and statistics which show their policies are damaging the life chances and killing poor and disabled people.”He added: “This poses a real challenge for the leaders of the disability rights movement and disabled people’s organisations in how to respond to politicians and civil servants who are not listening and aren’t interested in disabled people’s lives and human rights.”John McArdle, co-founder of Black Triangle, said: “This is yet another damning body of evidence that makes it clear that the UK government is guilty of implementing policies and systems that are leading directly to the deaths of hundreds, if not thousands, of chronically ill and/or disabled people.“It remains the case that there exists no safety protocol built into the DWP-Maximus [the US company which carries out the tests] disability assessment regime.“Vital medical evidence is neither sought by, nor provided to, the DWP and we are firmly of the view that this is a deliberate policy.“The Westminster government knows fine well that were such vital evidence to be provided, far fewer people would be found fit for work and so the Tories’ overarching goal of destroying our social security safety net as part of George Osborne’s ‘long-term economic plan’ would fail to meet its target.“Lives lost are accepted as being collateral damage in achieving this aim. These deaths have irrefutably arisen as a direct consequence of the implementation of an official policy that is ‘intentionally or knowingly reckless with a depraved disregard for life’.“The Westminster government is therefore unquestionably guilty of democide.”Michelle Maher, of the WOWcampaign and petition, said the research “joins a long list of evidence given to the government on the horrific impact of medical assessments”.She said: “I am still concerned that the government will claim they are listening and change the WCA, making it worse, under the heading of helping sick and disabled people into work because work is good for us.“The numerous reports into foodbanks have been ignored or justified in appalling ways, with Tory members celebrating their existence.“I fear the same will be said of the WCA and reports of the language the DWP and Iain Duncan Smith are using would indicate a direction of change that will be far worse.”The study’s authors say their findings also demonstrate the need for a cumulative assessment of the impact of austerity measures on disabled people, as demanded by the WOWcampaign.The study was published online in the Journal of Epidemiology and Community Health, and carried out by researchers from the University of Liverpool’s Institute of Psychology, Health and Society, and from the University of Oxford, and funded by the National Institute for Health Research, which itself is funded by the Department of Health.Ben Barr, the study’s lead author and senior clinical lecturer in applied public health research at the University of Liverpool, said: “The programme of reassessing people on disability benefits using the WCA was independently associated with an increase in suicides, self-reported mental health problems and antidepressant prescribing.“This policy may have had serious adverse consequences for mental health in England, which could outweigh any benefits that arise from moving people off disability benefits.”But DWP dismissed the report’s findings.A DWP spokesman said: “This report is wholly misleading, and the authors themselves caution that no conclusions can be drawn about cause and effect.“In addition, it is concerning that they provide no evidence that the people with mental health problems highlighted in the report even underwent a work capability assessment.”He pointed to the five independent reviews of the WCA – the first three carried out by Professor Malcolm Harrington – and “significant improvements to the process” made by DWP since 2010, including to how the WCA is used to assess people with mental health conditions.He also said the percentage of people with mental health conditions who receive the highest level of support after being assessed for eligibility for employment and support allowance through the WCA has “more than tripled since 2010”.Barr said DWP’s response was “disappointing”, and that none of the other factors researchers had looked at as possible causes, such as cuts to local government services or a fall in wages, could explain the rise in suicides and the deterioration in mental health.And he said the increases only happened among age groups most affected by the WCA, while the rise in mental health problems “tended to occur shortly after the increase in people undergoing the WCA in each area”.Barr also called on DWP to publish any data it has on claimants’ mental health before, during and after the assessment.He said: “Unfortunately, the DWP implemented the policy without a controlled trial or any plans to evaluate its impact on mental health. “Given that data is not currently available on the specific individuals who underwent the WCA and there is no trial evidence, the next best approach to investigate the potential effects on mental health is the one we applied in our study, using appropriate statistical methods to control for alternative explanations for these trends.  “Our findings should at the very least raise serious concerns for the DWP that the potential negative impacts of the WCA need to be investigated further.” Sue Bott, deputy chief executive of Disability Rights UK, added: “It is shameful for the DWP to dismiss in such an offhand manner a serious academic study showing a worrying rise in suicides and mental health issues connected to the WCA. “This evidence, added to the growing weight of evidence from tribunals and concerns from coroners, should surely lead to a complete rethink on the WCA, which by any measure is not fit for purpose.”*Crow’s own piece of work, We Are Figures, grew out of the discussions with Stuckler, but because of the difficulty of identifying how many austerity-related deaths there had been, she focused on the human cost of austeritylast_img read more

iPad Pro Gets a Bigger Screen But Comes at a High Price

first_img –shares Image credit: Apple Apple’s smallest iPad Pro is getting bigger.Speaking at WWDC on Monday, Apple CEO Tim Cook called the new 10.5-inch version the “perfect size” for the company’s flagship tablet. It replaces the 9.7-inch version, although Apple is keeping the 12.9-inch model, which it also refreshed at WWDC. Despite the larger screen, the 10.5-inch iPad Pro didn’t get any heavier than its predecessor — it still weighs about one pound. Inside, it’s powered by an A10X Fusion chip and includes the same cameras as the iPhone 7, which means a 12-megapixel main camera with optical image stabilization, along with a 7-megapixel front shooter. And since one of the iPad Pro’s chief advantages over the regular iPad is compatibility with the Apple Pencil, there’s also a redesigned Retina display that achieves smoother scrolling and drawing with the pencil thanks to 20-millisecond latency.If you’re editing video footage with your iPad Pro, the expanded screen real estate, better Pencil reaction times and A10X chip will likely make for a smoother experience. And if you’re editing video outside or in other challenging light conditions, you’ll appreciate that the display can automatically adjust its white balance to compensate. While that feature is also available in the previous generation, it’s another reason to chose the iPad Pro over the iPad.The main reason not to spring for the iPad Pro is, of course, its astronomical price, and that’s no less true with Monday’s update. If you’re a current 9.7-inch iPad Pro owner, you’ll need to replace your keyboard if you upgrade to the 10.5-inch model. Apple is offering a new $159 full-size Smart Keyboard that also doubles as a cover to fit the 10.5-inch iPad Pro.Add the keyboard and pencil ($99) to the $649 asking price for the 64GB Wi-Fi-only 10.5-inch iPad Pro, and you start to enter ultrabook territory, which means that even with a larger size, the base-model iPad Pro will have limited appeal among cost-conscious professionals. The refreshed 12.9-inch model, which gets the same internal improvements as its little cousin, starts at $799 for a 64GB Wi-Fi-only version. Both models can be ordered starting Monday with a cellular antenna for an additional $130. iOS 11 will bring additional capabilities to the iPad Pro when it rolls out this fall, including new multi-tasking features like drag and drop and an easier-to-use app picker menu. Apple Register Now » Add to Queue News reporter Free Webinar | Sept 5: Tips and Tools for Making Progress Toward Important Goalscenter_img Next Article This story originally appeared on PCMag iPad Pro Gets a Bigger Screen, But Comes at a High Price Tom Brant Attend this free webinar and learn how you can maximize efficiency while getting the most critical things done right. This fall, iOS 11 will also bring additional multi-tasking capabilities, like drag and drop.last_img read more

Should You Launch an ICO to Raise Money for Your Startup

first_img Guest Writer Learn how to successfully navigate family business dynamics and build businesses that excel. In the past few months, you’ve likely heard about initial coin offering (ICO) fundraising, as some startups have experienced a significant amount of funding this way. Could ICOs replace traditional venture capital?On the surface, ICOs appear to be the new, successful startup journey alternative. However, before making any hasty decisions, it is imperative that you understand how these two very different types of funding compare.Related: Basic Blockchain Lingo Every Entrepreneur Needs to KnowICOs have seen immense growth, but there are challenges.There’s been a significant amount of media coverage in relation to ICOs, especially as the blockchain and cryptocurrency industry evolves. However, taking a closer look, it appears that there are some critical gaps in the available information, which for many is misleading.Of course, there are advantages to this model, including more rapid funding and fewer regulations — which may actually be a double-edged sword. Unlike the traditional model, which requires startups to first build a company, generate revenue, and then get funding from angel investors (before landing a venture capitalist), ICOs provide somewhat of a shortcut.The growth of ICOs alone is enough to turn heads. In June of this year, ICOs surpassed $550 million in funding, which was more than what was raised through venture capital fundraising. However, these benefits are not enough to convince many partners and investors.Being an open, unregulated system, anything can happen, and when you’re dealing with millions of dollars, “anything” isn’t exactly what you want to hear. In fact, one of the primary concerns for investors is the ambiguity of utility tokens, resulting in varying rights. There are also a number of significant risks involved, including taxable proceeds.Related: 3 Things You Need to Know Before Starting Your Own ICOICOs simply are not ready to take over traditional venture capital. Here’s why.Although many support ICOs and blockchain technology overall, it is the general consensus that the technology itself is still immature, leading to many risk factors. In some countries, such as China, ICOs have been banned due to a lack of regulation, as well as a high rate of fraudulent and illegal activity.If you are considering the ICO market to fund your startup, please consider the following in relation to traditional venture capital.Poor liquidity. Although companies are raising real capital, without enough liquidity, the participation from buyers quickly outweighs the supports of market buyers. Strict regulations and the use of multiple currencies also contribute to poor liquidity.Quality control and increased risk of scams. One review, published by The Wall Street Journal, found that after analyzing 1,450 ICOs, 20 percent contained major red flags. This included plagiarized documents, fake executive teams and guaranteed returns.Higher failure rate. As of February 2018, 46 percent of the previous year’s ICOs had already failed — despite the fact that they had raised more than $104 million. This is resulting in what’s referred to as a “digital graveyard,” as many of these ICOs appear to have been doomed from the start.At the end of the day, the majority of ICO-funded startups are poorly managed and lack the required cash flow. Since the cash raised by an ICO doesn’t technically have any legal leverage, as they are not currently regulated, this option is risky for investors, as well as your reputation.Related: Want to Invest in an ICO in 2018? Here’s All You Need to Know.Token sales and the phenomenon surrounding ICOs certainly has potential, but it’s still in its infancy. It’s the new “Wild West,” and until some of the major kinks are worked out, venture capital is still largely the most promising route, as you will attract loyal investors while building valuable connections.Regardless, this is an industry that should be watched closely, as many industry leaders, including Bill Gates and John Donahoe, support the evolution of digital currency. Based on your current business model and business plan, are you unsure which option is best? 4 min read July 18, 2018 Register Now » Image credit: Peshkova | Getty Images Rahul Varshneya Add to Queue As of February 2018, 46 percent of the previous year’s ICOs had already failed — despite the fact that they had raised more than $104 million. –shares Opinions expressed by Entrepreneur contributors are their own. Next Article Should You Launch an ICO to Raise Money for Your Startup? Free Webinar | July 31: Secrets to Running a Successful Family Business Technology Co-founder at Arkenealast_img read more

Bill Gates Says These Tech Innovations Will Change the World

first_img Register Now » February 28, 2019 The billionaire philanthropist weighed in on the scientific advances that he believes will make an impact in 2019 and beyond Attend this free webinar and learn how you can maximize efficiency while getting the most critical things done right. Bill Gates has made his fortune, and has given much of it away, thinking about the endeavors that will make our the world a healthier, connected and equitable place. Recently, the MIT Technology Review asked the Gates Foundation and Microsoft co-founder to share the inventions and technologies that he believes will effect real change this year and beyond.Some of the advances he offered up include projects such as Dactyl, which teaches robots how to develop fine motor skills like flipping a block in its hand, and work being done to develop machines that could pull carbon dioxide from the air to lessen the effects of climate change.Given his interest in improving conditions around the world, it’s unsurprising that most of the innovations on Gates’s list focus on wellness.Related: Bill Gates Made These 15 Predictions Back in 1999 — and It’s Scary How Accurate He WasSome of these include green toilets that can get rid of waste and treat water at the same time, plant-based meat alternatives that are developed in the lab, customized cancer vaccines tailored to an individual patient’s needs and a capsule with a mini microscope attached to it that would allow physicians to check kids and infants for gut issues without having to use anesthesia.Looking even further ahead to the future, Gates shared what we wanted to see on his potential list 20 years from now.“I would hope to see technologies that center almost entirely on well-being. I think the brilliant minds of the future will focus on more metaphysical questions: How do we make people happier? How do we create meaningful connections? How do we help everyone live a fulfilling life?” Gates wrote. “I would love to see these questions shape the 2039 list, because it would mean that we’ve successfully fought back disease (and dealt with climate change). I can’t imagine a greater sign of progress than that.” Bill Gates Says These Tech Innovations Will Change the World Bill Gates –shares Next Article center_img Staff Writer. Covers leadership, media, technology and culture. 2 min read Image credit: Thierry Monasse | Getty Images Nina Zipkin Free Webinar | Sept 5: Tips and Tools for Making Progress Toward Important Goals Add to Queue Entrepreneur Stafflast_img read more

Updates Make Uber More Accessible to the Deaf Start Up Your Day

first_imgStart Up Your Day April 20, 2016 Image credit: Shutterstock | Enhanced by Entrepreneur –shares 2019 Entrepreneur 360 List Entrepreneur Staff Add to Queue Entrepreneur Staffcenter_img 1 min read Updates Make Uber More Accessible to the Deaf – Start Up Your Day Roundup Next Article Looking for the latest headlines in small business, innovation and tech? Our Start Up Your Day recaps are posted every morning to keep you current. Accessible. And update makes Uber more accessible to deaf drivers and passengers.  Super users. Facebook might start paying some users, says Fortune. Slipping. Yahoo’s sale can’t come quickly enough. This past quarter it posted a double digit loss. One of a kind. Each city has it’s own microbe signature, according to a new study.   About the other night. Customer whose midnight McDonald’s story went viral has a confession: He made it up. Good bit in the eighties. The Commodore 64 is having a comeback — with some important updates.  The only list that measures privately-held company performance across multiple dimensions—not just revenue. Apply Now »last_img read more

Researchers uncover how the immune system protects from bowel cancer

first_img Source:https://www.charite.de/en/service/press_reports/artikel/detail/wie_das_immunsystem_vor_darmkrebs_schuetzt/ Reviewed by Alina Shrourou, B.Sc. (Editor)Jan 31 2019Researchers from Charité – Universitätsmedizin Berlin have discovered a protective mechanism which is used by the body to protect intestinal stem cells from turning cancerous. The body’s innate immune system was found to play a pivotal role in this regard. The researchers were able to demonstrate that, rather than having a purely defensive role, the immune system is crucial in maintaining a healthy body. The study has been published in the renowned scientific journal Nature.Inside our bowels, there is a meeting of two worlds. It is where the cells of our intestinal cell walls meet foreign materials, such as bacteria, foodstuffs, and the breakdown products of digestion. Both of these worlds – that of our bodies and that of the outside world – are in direct contact, continually exchanging information. This direct contact is of crucial importance to our bodies, as many of the environmental factors we are exposed to (such as certain types of bacteria or essential nutrients) are beneficial or even vital to our health. However, contact with the environment can also have a negative impact on our bodies. Certain foreign substances, for instance, can trigger genetic changes inside the epithelial cells which line our intestinal walls. The accumulation of this type of DNA damage, particularly when it occurs inside epithelial stem cells, can lead to bowel cancer.To prevent this progression to cancer, cells have the capacity to repair DNA damage. Where damage is too extensive, they can commit ‘altruistic cell suicide’ (also known as apoptosis). Until now, scientists had assumed that stem cells triggered this repair mechanism independently. However, the study (led by Prof. Dr. Andreas Diefenbach, Director of Charité’s Institute of Microbiology, Infectious Diseases and Immunology, BIH-Professor in Precision Medicine and Head of the Mucosal Immunology Research Group at the German Rheumatism Research Center) comes to a different conclusion, namely that the immune system is capable of enhancing the DNA repair mechanism in damaged stem cells, thus preventing progression to bowel cancer.Related StoriesLiving with advanced breast cancerUsing machine learning algorithm to accurately diagnose breast cancerBacteria in the birth canal linked to lower risk of ovarian cancerWorking with other researchers, Prof. Diefenbach and his team were able to show in a mouse model that cells of the innate immune system are capable of recognizing genotoxic environmental factors present in the bowel. Among these are certain glucosinolates, natural components of plants which are commonly found in many types of cabbage. Once the cells of the innate immune system detect damaging glucosinolates, they send out interleukin 22, a type of cellular messenger. This, in turn, enables the epithelial stem cells to detect potential DNA damage earlier and repair it faster. “The immune system acts like a sensor that detects genotoxic food components,” explains Prof. Diefenbach. “Switching off this sensor results in a significant increase in cases of bowel cancer.”For the immunologist, these findings are not only evidence of a previously unknown regulatory system which is used by the body to protect itself against bowel cancer. It is also evidence of the fact that the immune system’s functions are far more complex than that of a simple defense mechanism against pathogens. “The immune system monitors both the healthy growth and function of different organs in the body,” explains Prof. Diefenbach. He and his team would like to use future research studies to explore the complex interaction between food components, intestinal flora, the intestinal wall and the immune system in greater detail. “It is here that we may find the key to why there are so many inflammatory disorders,” says Prof. Diefenbach.last_img read more

Lenovo posts firstquarter profit as recovery continues

first_img Citation: Lenovo posts first-quarter profit as recovery continues (2018, August 16) retrieved 18 July 2019 from https://phys.org/news/2018-08-lenovo-first-quarter-profit-recovery.html Chinese technology giant Lenovo Thursday recorded a sharp rise in first quarter net profit as the company’s turnaround gathered pace. Lenovo posts $189 mn full-year loss on one-time write-off The PC maker posted a $77 million net profit in the quarter to June 30—up from a $72 million loss in the same period last year.”The Group remains confident in its core PC business, and aims to grow … without compromising on profitability,” chairman Yang Yuanqing said in a statement.Analyst Jackson Wong said competition between PC makers “is not as fierce as it is in the mobile sector”, while Lenovo’s focus on hardware has also contributed to the positive results.Lenovo also reported a 19 percent rise in revenue to $11.91 billion—its second consecutive quarter of double-digit revenue growth.The tech giant is turning its fortunes around following a $189 million net loss for the full fiscal year, dragged down by a $400 million non-cash write-off charge from deferred income tax assets.The company’s shares rose up to six percent to HK$4.72 mid-morning after the results were released. © 2018 AFP Explore further This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.last_img read more

Apple profit stable as service gains offset iPhone slump

first_img © 2019 AFP Profit in the final quarter of last year was $20 billion—a dip of less than one percent—on revenue of $84.3 billion, even as money from iPhone sales was down 15 percent from the same period in 2017.The full extent of the slump in iPhone sales was not clear because Apple for the first time stopped reporting unit sales for its iconic smartphones.Overall revenue for Apple dipped nearly five percent from a year ago, in line with the lowered guidance earlier this month that stunned the market and hammered shares of the iPhone maker.”While it was disappointing to miss our revenue guidance, we manage Apple for the long term, and this quarter’s results demonstrate that the underlying strength of our business runs deep and wide,” chief executive Tim Cook said in the earnings release.The update for Apple’s first fiscal quarter to December 29 was greeted with relief on Wall Street, as shares rallied 5.75 percent in after-hours trade.Pressure to diversifyApple had been under pressure to show it can weather the slump in the global smartphone market and diversify its revenue base, and the latest results appeared to satisfy the market.Services revenue reached an all-time high of $10.9 billion, up 19 percent over the prior year. Apple also boosted sales of wearables and accessories by 33 percent from last year.Cook has long emphasized the potential of that side of Apple’s business.”Our active installed base of devices reached an all-time high of 1.4 billion in the first quarter, growing in each of our geographic segments,” Cook said.”It’s driving our Services business to new records thanks to our large and fast-growing ecosystem.”An Apple streaming music service launched in mid-2015 now boasts more than 50 million subscribers. Citation: Apple profit stable as service gains offset iPhone slump (2019, January 30) retrieved 17 July 2019 from https://phys.org/news/2019-01-apple-profit-stable-gains-offset.html Apple said revenue from iPhone sales dropped by 15 percent from a year ago but did not offer details on unit sales Apple said Tuesday that profits held steady in the most recent quarter, with revenue growth in music, movies, apps and other services offsetting slumping iPhone sales, sparking a rally in shares of the California tech giant. “We will participate in the original content world,” Cook said while discussing Apple’s plans for video content.”We have signed a multi-year partnership with Oprah,” he said, adding that Apple has hired “some great people” whom he is confident in.Losing steam?Apple took a hit in the “Greater China” region, where revenue plunged almost 27 percent, which had been expected following the company’s latest revenue warning.While Apple appeared to avoid the worst with its latest results, the long-term outlook is less certain, some analysts say.”While Apple is still a money-making machine, today’s uncharacteristic revenue decline symbolizes a company that is starting to run out of steam,” said Neil Saunders of the research firm GlobalData Retail.”In our view, this is something to be corrected, not least because Apple is a costly company to run and it relies on strong revenue growth to drive up the bottom line.”Cook contended weak economic conditions in China hurt iPhone sales, but said Apple had record services revenue there despite game apps facing difficulties getting approved by regulators.Saunders said the problems with iPhone sales and China pose significant threats to Apple’s future.”Apple is fortunate in having a strong base of fans and many consumers who are bought into its ecosystem of services,” Saunders said.”But without device innovation, even this will be insufficient to maintain iPhone market share in the face of rising competition.” Apple shares slide after disappointing holiday outlook Explore further And the California-based company looks to build momentum for its Apple TV service, with deals to have it installed on television models coming out this year.During the earnings call, Cook confirmed that Apple plans to produce its own shows in a move that could challenge streaming television giants Netflix and Amazon Prime, which have invested heavily in original content. Apple met its recently lowered guidance for the most recent quarter, sparking a rally in after-hours trade This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.last_img read more