“After several years of tough negotiation, the institutions and detailed procedures of the Kyoto Protocol are now in place,” said Michael Zammit Cutajar, the Convention’s Executive Secretary. “The next step is to test their effectiveness in overseeing the 5 per cent cut in greenhouse gas emissions by developed countries over the next decade.” Speaking in Marrakech at the 7th annual meeting of the Conference of the Parties to the climate change Convention, Mr. Zammit Cutajar said important progress had been made on strengthening the flow of financial and technological support to developing countries, to help them move toward a sustainable energy future. The Marrakech meeting, held from 29 October to 9 November, sent a clear signal to business, local governments and the general public that climate-friendly products, services, and activities will be rewarded by consumers and national policies alike, said Mr. Zammit Cutajar, who after 10 years in his post will be stepping down at yearend. The meeting also adopted the Marrakech Ministerial Declaration as an input into next September’s World Summit on Sustainable Development in Johannesburg, South Africa. The Declaration emphasizes the contribution that action on climate change can make to sustainable development and calls for capacity building, technology innovation, and cooperation with the biodiversity and desertification conventions. The 1997 Kyoto Protocol will enter into force and become legally binding after it has been ratified by at least 55 Parties to the Convention, including industrialized countries representing at least 55 per cent of the total 1990 carbon dioxide emissions from this group. So far, 40 countries have ratified, including one industrialized country (Romania). Many governments have called for the entry into force to take place in 2002. The Marrakech conference was attended by 171 governments and a total of some 4,500 participants. Next year’s meeting, which India has offered to host, will be held from 23 to 1 November.
Responding to questions about a statement issued Friday on behalf of Secretary-General Kofi Annan concerning the incident, Hua Jiang said, “The information available to us when the statement was issued was that the victims were Israeli civilians returning from religious service.”“Subsequently, it now appears that the Israeli victims were in fact soldiers and security personnel,” she noted.The Secretary-General, who remains “deeply concerned” about the continuing spiral of violence in Israel and the Occupied Palestinian Territory, “continues to believe that only a comprehensive solution developed through a process that addresses political, security, humanitarian and economic issues in parallel can ensure real security for both the Israelis and the Palestinians,” Ms. Jiang stressed.
MILWAUKEE — Catcher Erik Kratz and the Milwaukee Brewers have agreed to a one-year contract that avoided salary arbitration.Kratz hit .236 with six homers and 23 RBIs in 219 plate appearances. The 38-year-old had a $1 million salary and earned $75,000 in performance bonuses based on plate appearances. He also excelled in Milwaukee’s division series win over the Colorado Rockies, going 5-for-8 in two games.His deal was announced Tuesday, three days before the deadline for teams to offer 2019 contracts to unsigned players on their 40-man rosters.___More AP MLB: https://apnews.com/MLB and https://twitter.com/AP_SportsThe Associated Press
The children’s grandmother has now appealed for the Government to intervene and return the children to the safety of the UK, along with their mother. Today they languish with their mother in a bleak refugee camp in Syria, their father’s dreams in tatters and their own future uncertain. Little Khadijah Ali was just one-year-old when her mother Nicole Jack took her off to join Islamic State’s brutal ‘Caliphate’. Her sister Somaiya was only three, while Naima was just six and their brother Isaac, the eldest, was only nine. Charleen Jack-Henry,… Together they were dragged from their home in west London in pursuit of their father Hussein Ali’s warped dream of a hardline Islamist paradise on earth.
DID YOU KNOW that there are Irish Defence Forces personnel currently posted in 20 different countries across the world?Some of those dreaming of home from farflung missions in Mali, Ivory Coast, Bosnia, Afghanistan and beyond have been sending photos and Christmas messages to loved ones here.The slideshow below is just a small selection – if you’d like to see more, see the messages from those at 42 Infantry Group at UNIFIL in the Lebanon by clicking here. For other smaller missions, click here.(Tomorrow, we’ll bring you the link to messages from those posted in Golan Heights, Syria.)
DAYS AFTER AN unofficial strike broke out at the Greyhound Household plant in Clondalkin, west Dublin, SIPTU has served seven days strike notice on the company.It said today that the workers “have been prevented from attending work under their current terms and conditions of employment since 6am on Tuesday, 17 June”.Unofficial strikeOn Tuesday 17 June, Greyhound Household said that it regretted the unofficial industrial action taken that morning by its household collection crews. It said that it was taking measures so that customers were not affected.It said that when staff came to work on Tuesday, they were asked to clock in “under the conditions recommended by the Labour Court”. However, they did not clock in and “refused to work under the new conditions” so they were asked to leave, said a spokesperson.On the same day, a man was taken to hospital by ambulance after an incident at the Greyhound Knockmitten Lane depot in Clondalkin. The company said it at the time it was investigating whether the man was knocked down.Official strikeSIPTU Organiser, Henry O’Shea, said today that strike notice has been served and will come into effect at 6am on Friday 27 June. Our members have been forced into this action because of the company’s unilateral imposition of terms and conditions of employment that have not been agreed and contain up to 35% pay cuts. They also contain changes to sick pay, bonuses, meal allowances and other conditions of employment.SIPTU has 70 members in the company which has a contract to collect household waste for Dublin City Council.Read: Truck ‘strikes Greyhound worker’ during unofficial industrial action>
Want to see the world’s thinnest 10-inch tablet in action? The folks at Diginfo.tv were lucky enough to spend some quality time with a Sony spokesperson and the Xperia Tablet Z, the company’s 6.9mm thick wonderslab.Sony’s understandably excited about the Xperia Z. The showfloor presentation keys in on its portability, which Sony says is all about the thin profile and light weight. At roughly seventeen ounces, it’s almost a half a pound lighter than the iPad. Sony says that makes the Xperia Tablet Z easy to slip into a bag without it becoming a burden. That’s assuming your satchel of choice is large enough to accommodate a 10-inch diagonal slate, of course.If you thought that the water resistant and dustproof properties of the Xperia Z devices were the only tricks up their sleeves, think again. It turns out Sony has designed the tablet and phone to be perfect companion devices. This goes way beyond NFC tap interactions, though those are supported. Sony has actually built one positively genius new feature into the tablet.Hook up the custom micro USB cable, and you can actually charge your Xperia Z phone from the tablet’s battery. Sony‘s already taken some heat for the 6000mAh capacity, but if it allows the Xperia Tablet Z to be this small and light and still act as an emergency power source for your phone, then it’s well worth the drop in endurance.Let’s face it, if you have to pick one device in your bag to have power it’s going to be your phone. Your tablet — especially if it’s Wi-Fi only — won’t do you any good if you need to call a cab, a tow truck, or 911.More at DigInfo.tv and Xperia Blog
As with all cases, I have also carefully considered whether the public interest requires prosecution through the courts. Particular consideration was given to Soldier B’s ill health, regarding which an updated medical report was obtained. In line with our Code for Prosecutors, I have concluded, given the seriousness of the charges, that the Public Interest Test for Prosecution is also met.“I have therefore taken the decision to prosecute an individual identified as Soldier B for the offence of murder in relation to the death of Daniel Hegarty and for the wounding of Christopher Hegarty,” Herron added.An inquest into Hegarty’s death in 2011 found that the boy “posed no risk” when he was shot. The decision to press charges now reverses a previous decision not to prosecute any soldier over his death. Last month, the PPS announced that a former British soldier is set to be charged in relation to two murders in Derry on Bloody Sunday in January 1972.SDLP Leader Colum Eastwood MLA welcomed the decision by the Public Prosecution Service to proceed with a case against ‘Soldier B’ for the murder of Daniel Hegarty and wounding of his cousin Christopher. The Foyle MLA said that the Hegarty family “deserve justice and accountability” for what happened to Daniel. https://jrnl.ie/4592464 Monday 15 Apr 2019, 2:46 PM Apr 15th 2019, 2:46 PM Troops moving in during Operation Motorman Tweet thisShare on FacebookEmail this article By Sean Murray Share232 Tweet Email2 Troops moving in during Operation Motorman Image: PA Archive/PA Images Former British soldier to face murder charge over 15-year-old boy shot dead in Derry in 1972 Daniel Hegarty was shot twice in the head on 31 July 1972. A BRITISH SOLDIER who shot dead a 15-year-old boy in Derry on 31 July 1972 is to be charged with murder, the Public Prosecution Service has said. The family of Daniel Hegarty were informed today of the decision to press charges against the soldier – identified as Soldier B. Hegarty was shot twice in the head during Operation Motorman, which saw thousands of British soldiers enter “no go areas” in Belfast and Derry.His cousin Christopher Hegarty, who was 17 at the time, was also shot and injured in the incident.After meeting the Hegarty family today, director of public prosecutions in the North Stephen Herron said he had given “careful consideration” to all available evidence before reaching his decision. Image: PA Archive/PA Images No Comments Short URL 17,910 Views
https://jrnl.ie/4597772 Image: Shutterstock/Epitavi Image: Shutterstock/Epitavi 1 Comment 10,474 Views Updated Apr 18th 2019, 8:51 AM EVERY MORNING, TheJournal.ie brings you the stories you need to know as you wake up.1. #DISCRIMINATION AIB has been criticised after a woman claimed staff at a Dublin branch made an assumption about her race when she tried to set up an account. 2. #TIPPERARY A man in his 50s was killed in a road traffic collision on the N24 from Clonmel to Carrick-on-Suir last night. 3. #MADEIRA The death toll from a bus crash on the Portugese island of Madeira has risen to 29, after a woman died from her injuries in hospital.4. #FAMILY HUBS Children have expressed feelings of sadness, confusion and anger at having to live in homeless family hubs, a new report to be published today will reveal. 5. #MEDIA DIVERSITY Ireland’s highly concentrated media ownership is the “single largest threat” to press freedom in the country, an international group has warned.6. #ROCKET MAN North Korean leader Kim Jong-Un has overseen the test-firing of a new tactical weapon with a “powerful warhead”, the country’s state media has reported.7. #MUELLER TIME A version of US Special Counsel Robert Mueller’s final report on Russian meddling in the 2016 election is set to be released to Congress today.8. #FINE MARGINS Dublin City Council forfeited almost €90,000 in unpaid library fines in 2018 in an effort to boost memberships, newly released figures have shown.9. #WEATHER Very mild and warm conditions will develop across the country, especially in western parts, as top temperatures reach between 14 and 20 degrees Celsius. Thursday 18 Apr 2019, 8:51 AM The 9 at 9: Thursday Here’s all the news you need to know this Thursday morning. Apr 18th 2019, 7:57 AM By Stephen McDermott Short URL Share1 Tweet Email Tweet thisShare on FacebookEmail this article
An agreement had been reached to sell the house to an unidentified buyer for more than €19 million. https://jrnl.ie/4803245 Image: Google Earth 32,980 Views Member of British House of Lords loses tenancy battle over Kilkenny mansion The court had been told that the managers of the trust for two of Magan’s children have decided to sell the mansion. Share7 Tweet Email3 Tue 1:46 PM THE HIGH COURT has ruled today that Lord Magan, a member of the British House of Lords, is not entitled to a new tenancy of the €20 million Castletown Cox mansion and 500 acre estate in Kilkenny which he had put in a trust for the benefit of two of his three children, Edward Magan and Henrietta Black.Mr Justice Tony Hunt made the declaration at a sitting of the Commercial Court in the absence of Lord Magan today. He had claimed that the Jersey-based trust for two of his children had taken unlawful possession of the house in a dawn raid in May last year while the house was vacant.Lord Magan, reported to have been worth tens of millions prior to the financial collapse of banks and other institutions 10 years ago, had rented the property back from the trust for an annual rent in the region of €100,000.He had fallen into arrears of more than €570,000 and the courts had granted a judgment against him for that amount in favour of Castletown Foundation Limited which was handling his children’s inheritance through the Jersey trustees.Magan and his son, Edward, who latterly handled correspondence relating to the legal proceedings against his father, were not in court to hear Judge Hunt’s decision. They had taken little part in proceedings after several legal teams had withdrawn from the case.Judge Hunt said today that Lord Magan had reached a stage where he was unable to pay his lawyers, and there was some evidence of a legal move having been made against his residence in London.The court had been told by Mr Rossa Fanning SC, who appeared with barrister Stephen Dowling for the foundation, that the trust managers, Yew Tree Trustees, Jersey had decided to sell Castletown Cox. This decision had been taken after borrowings secured on the property by a finance company reached more than €14 million.An agreement had been reached to sell the house to an unidentified buyer for more than €19 million but the purchaser had insisted on vacant possession, leading to a successful application to have Lord Magan evicted for non-payment of rent.Lord Magan, a life peer and a former treasurer of the Conservative Party in the UK, had claimed he was entitled to a renewed tenancy which Judge Hunt dismissed today.Judge Hunt awarded costs against Lord Magan. Tuesday 10 Sep 2019, 1:46 PM No Comments An agreement had been reached to sell the house to an unidentified buyer for more than €19 million. Image: Google Earth Short URL By Ray Managh Tweet thisShare on FacebookEmail this article
Des oiseaux colossaux vivaient parmi les dinosauresLa découverte d’un énorme os de mâchoire au Kazakhstan fournit une preuve supplémentaire de l’existence d’oiseaux géants à l’époque des dinosaures.Un oiseau doté d’un crâne de 30 centimètres de long. C’est ce que vient tout juste de découvrir au Kazakhstan une équipe de chercheurs dont certains de l’université de Portsmouth au Royaume-Uni. En vérité, c’est plutôt la mâchoire de l’animal qu’ont mis au jour les scientifiques. Mais en étudiant le fossile, ils sont parvenus à évaluer les dimensions de l’oiseau gigantesque baptisé Samrukia nessovi. Ainsi, ils ont établi que si l’oiseau ne pouvait pas voler, il mesurait peut-être deux à trois mètres de haut. En revanche, s’il pouvait voler, son envergure atteignait probablement quatre mètres pour un poids estimé à 50 kilogrammes.À lire aussiComment connait-on la couleur des dinosaures ?Dans leur étude publiée dans la revue Biology Letters, les scientifiques indiquent alors que ce fossile prouve une nouvelle fois l’existence d’oiseaux gigantesques à la période du Crétacé. Car ce n’est pas le seul ossement de la sorte qui a été trouvée. Un premier fossile de colonne vertébrale avait déjà été découvert en France en 1995. Si la grande majorité des oiseaux du Crétacé ne devaient pas dépasser la taille d’un corbeau, le Dr Darren Naish, l’un des auteurs de la trouvaille, souligne néanmoins que ce second fossile suggère que les grands oiseaux n’étaient pas aussi rares qu’on le croyait jusque là. Une cohabitation avec les dinosaures “On ne connait ce fossile que par sa mâchoire inférieure, malheureusement nous ne pouvons donc rien dire avec certitude sur la forme de l’animal entier”, a expliqué à la BBC le Dr Naish avant de préciser que l’oiseau pouvait très bien ressembler à une autruche, un albatros ou un condor, selon ses capacités de vol. Mais outre la forme de l’animal, d’autres interrogations demeurent cette fois-ci, sur les congénères de ces oiseaux.”Je pense que l’élément véritablement intéressant est le fait que ces oiseaux vivaient aux côtés des dinosaures géants que nous connaissons de cette période : les tyrannosaures, les sauropodes au long cou, les dinosaures à bec de canard. Cela appelle de nombreuses questions concernant les interactions écologiques existantes entre ces différents animaux”, commente le chercheur avant de conclure : “si certains prétendaient qu’il n’y avait pas de grands oiseaux lorsque vivaient de grands ptérosaures, nous savons maintenant qu’il n’en est rien”.Le 12 août 2011 à 18:21 • Maxime Lambert
Exclusive Interviews – Oscars buzz is rising at the Toronto Film Fest NXT Highlights: Johnny Gargano addresses NXT future, Baszler vs. Ripley, Pete Dunne in action Kim Kardashian ‘Got in Trouble’ With Kanye For Daughter North Wearing Makeup Pinterest Google+ Exclusive Interview: Rosario Dawson doesn’t need coffee to be upbeat in the morning Facebook Now Playing Up Next Now Playing Up Next NXT talents Devin Taylor and Cal Bishop were released by WWE on Friday morning. Taylor was being used as a backstage interviewer, while Bishop wasn’t being used often.Source: PWInsider.comRecommended videosPowered by AnyClipKim Kardashian ‘Got in Trouble’ With Kanye For Daughter North Wearing MakeupVideo Player is loading.Play VideoPauseUnmuteDuration 0:31/Current Time 0:00Loaded: 100.00%0:01Remaining Time -0:31 FullscreenUp NextThis is a modal window.Beginning of dialog window. Escape will cancel and close the window.TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal DialogEnd of dialog window.Replay the list Videos Articles Jenna Fischer, Angela Kinsey Launching ‘Office’ Podcast Now Playing Up Next Adam Martin RELATED ARTICLESMORE FROM AUTHOR Now Playing Up Next WhatsApp Kendall Jenner opens up about her insecurities Now Playing Up Next WALTER and Kassius Ohno set to compete at EVOLVE 135 and 136 Live Events Kanye West 9/13 NXT Live Results: Cocoa, FL (Dain vs. Kushida, NXT North American Title Match) Twitter
Lawn chairs and blankets cover the grassy slope of the Columbia Tech Center Park.The sun is shining, but the breeze keeps it feeling cooler. People shuffle between their grass swaths and the vendors selling hot foods and shave ice.It’s a few minutes before 6 p.m., and the east Vancouver park is filling up. Ryan Euverman and his family spot their friends in the crowd and set up in the open space next to them.This is the second Sunday evening Euverman and his wife and daughters have made the short drive to their neighborhood park to take in a free concert — part of the Columbia Tech Center Sunday Sounds summer concert series hosted by the city of Vancouver.“We love it,” Euverman said. “The weather’s been great. The bands are good. It’s close, which is nice.”“This park is a fantastic place to host this,” he added.Tucked along Tech Center Drive, the park sits behind the Parkside Lofts apartments. An inflatable bandshell is set up on a concrete stage; the audience fills the grass terrace and open green space stretching back to the street.The city of Vancouver partnered with Columbia Tech Center, which owns the park, to host the concert events, beginning in 2015.“Our main reason for doing it was we do a lot of city-sponsored events in the downtown area, and we wanted to get out east,” said Stacey Donovan, special events manager for the city.
Facebook Twitter Google+LinkedInPinterestWhatsAppPUBLIC NOTICENOTICE OF AGRICULTURAL PRODUCT RECALLThe Turks and Caicos Islands Department of Agriculture and the Environmental Health Department are conjointly issuing a product recall notice to the general public.On October 12, 2014, SunBurst Foods, Goldsboro NC, USA voluntarily issued a recall of all of its SunBurst Fresh Bites and Private labeled products which are currently in the market because these products have the potential to be contaminated with Listeria monocytogenes, an organism which can cause serious and sometimes fatal infections in young children, frail or elderly people, and others with weakened immune systems. Although healthy individuals may suffer only short-term symptoms such as high fever, severe headaches, stiffness, nausea, abdominal pain and diarrhea; Listeria infection can cause miscarriages and stillbirths among pregnant women.All codes, all sell-by dates and sizes of the following brands are being recalled:· SunBurst·Fresh BitesPrivate label products are identified by the following brand names:· River Edge Farms· CFW· Southern Zest· CJ’s Vending· Binford Street Deli· Middle Georgia Vendors· Roanoke Foods· Select Foods· Jesse JonesThe products being recalled were sold in North Carolina, South Carolina, Virginia, and Georgia. The recall was initiated as a result of sampling and testing performed by the North Carolina Department of Agriculture and Consumer Services.To date, there have been no reported illnesses related to these products. However, the Turks Caicos Government Islands Department of Agriculture and Environmental Health Department are urging consumers, who have purchased the affected products to desist from eating them and destroy or return them to the place of purchase for a refund. Distributers within the Turks and Caicos Islands are urged to contact their suppliers immediately.Persons who suspect that they might have consumed any of the affected products and are feeling unwell are advised to visit a medical facility immediately.Importers of agricultural produce are also advised to pay close attention to the notice and to ensure that their consignments destined for importation are untainted.Below is a list of the recalled products with their Manufactured Number (MFG) and Universal Product Codes (UPC).Manufacture Number Product Description Universal Product Code1636 Potato Wedges 7-01248-00924-31740 Caesar Salad 7-01248-01028-71739 Garden Salad 7-01248-01027-01729 Apple Cobbler 7-01248-01041-61749 Blueberry Crunch Cake 7-01248-01037-91750 Cherry Crunch Cake 7-01248-01038-61738 Jello with Fruit 7-01248-01026-3659 Peach Cobbler 7-01248-00848-2648 Strawberry Shortcake 7-01248-00549-81783 Grapes 7-01248-01068-31789 Honeydew Melon 7-01248-01074-41788 Pineapple 7-01248-01073-71782 Strawberries 7-01248-01067-61790 Watermelon 7-01248-01075-11522 Caesar Salad 7-01248-00623-51502 Chef Salad 7-01248-00603-7280 Garden Salad 7-01248-00323-4The above notice is issued conjointly between the Department of Agriculture and the Environmental Health Department. Interested persons are free to contact the respective Departments for further information at telephone numbers 649-338-2143, 649-338-2144, and /or 946-5801 respectively and email address firstname.lastname@example.orgENDGovernment Press OfficeWaterloo Road, Grand TurkTurks & Caicos IslandsTel: (649) 338-3924/ 338-3925Ext: 3924/3925Email: email@example.comWeb: gov.tc/pressofficeWe are on Facebook: www.facebook.com/pressofficetcig Facebook Twitter Google+LinkedInPinterestWhatsApp Related Items:agricultural products, Environmental Health Department, north carolina department of agriculture and consumer service, recall, sunburst foods, Turks and Caicos Islands Department of Agriculture TCIG ready to spend to stop Zika Recommended for you Salmonella contamination forces Dole Spinach recall Plastic plagued Purdue Nuggets taken off TCI store shelves
(Alaska Division of Motor Vehicles)Starting Thursday, Alaskans will be able to get license plates with bears on them.Download AudioThe Division of Motor Vehicles has brought back a 1976 license plate that was originally issued for the United States’ bicentennial. The updated plate features a grizzly reared up against a sunset backdrop.Right now, the standard license plate in Alaska is solid yellow, with an Alaska flag in the center and the words “The Last Frontier” below. DMV Director Amy Erickson expects the bear plates to be a popular alternative.“We’re anticipating that most people are going to select the bear over the ‘Last Frontier’ now,” says Erickson.Erickson says she plans to keep her Last Frontier license plate. But retired legislator Peggy Wilson, who sponsored the bear plate bill last year, says she plans to change hers immediately. The Wrangell Republican says the grizzly design is a conversation starter, particularly for Alaskans roadtripping outside the state.“When you are from Alaska, people just want to talk about Sarah Palin,” says Wilson. “And now, this is something else — the license plate, it gives them another conversation starter.”Wilson says the original idea for the bear plate legislation came from a constituent, who once had the original version on his car. That constituent will be the first person to be issued the new plates.Drivers seeking to swap their Last Frontier plates for the grizzly design can do so for $5.
National Park Service rangers are investigating the shooting death of a moose inside Denali National Park in violation of federal law.Download AudioCow moose (Wikicommons photo by Veronika Ronkos)The cow moose was found Tuesday near the Denali post office.The moose’s calves, which are about three weeks old, remain in the area.People in the park are allowed to carry guns and can shoot moose to defend themselves but must report the incident. No report has been filed.Park officials say they have no plans to rescue the calves.The agency says they’re too nimble to catch easily and trying to catch them would be dangerous for the animals.They say that if the calves weaken enough to be caught safely, they will be captured and transferred to a rearing facility.
A drug that stops the spread of cancer has been developed, with scientists identifying the cells responsible for initiating and promoting metastasis. While the drug has only been tested on mouse models, researchers are hopeful the discovery will have widespread applications for future cancer treatments.Metastasis the process through which cancer spreads from one part of the body to another. It is one of the aspects of the disease that makes it so deadly – indeed, it is the reason behind 90% of human cancer deaths. The process by which cancer spreads is extremely complex. The cells that trigger metastasis are not known, so the development of therapies to prevent it is challenging.However, a team of researchers led by Gloria Pascual of the Institute for Research in Biomedicine (IRB Barcelona) has now found these cells, and shown how they can be used to stop the spread of cancer.In a study published in the journal Nature, the team found a specific protein – CD36 – in the membranes of tumour cells that are responsible for taking up fatty acids (a receptor). The team discovered CD36+ cells in samples of human oral carcinoma (oral cancer).When CD36 was absent from the tumours, they did not develop metastasis. When it was added, the tumours became metastatic.Researchers then looked at CD36 in mouse models of oral, melanoma and breast cancer. After treating them with antibodies to block the receptor, metastasis was either significantly reduced or totally eliminated. Furthermore, metastases already present shrunk or disappeared. Where matastases was already established, the treatment removed it in 20% of the cases, and reduced it in between 80-90% of the remainder. There were no significant side-effects observed.Cancer metastasis dependent on fat? Because CD36 is responsible for the uptake of fatty acids, the researchers looked at what role fat intake has on the spread of cancer. To do this, they provided one group of mice with a high-fat diet and inoculated them with oral cancer. In the control group, 30% went on to develop metastasis, compared to 80% of the high-fat group. This indicates a high-fat diet increases the risk of metastasis.Aznar Benitah said: In mice inoculated with human tumour cells, there appears to be a direct link between fat intake and an increase in metastatic potential through CD36. More studies are needed to unravel this intriguing relationship between diet and metastasis, above all because industrialised countries are registering an alarming increase in the consumption of saturated fats and sugar.Fat is necessary for the function of the body, but uncontrolled intake can have an effect on health, as already shown for some tumours such as colon cancer, and in metastasis, as we demonstrate here.Further analysis showed metastasis is also dependent on CD36 in ovarian, bladder and lung cancer. Findings indicate there could be a general mechanism that underlies metastasis – and treatments that block CD36 could be key to stop the spread of cancer.Although we have not yet tested this in all tumour types, we can state that CD36 is a general marker of metastatic cells, the first marker I know of that is generally specific to metastasis, said Salvador Aznar Benitah, head of the Stem Cell and Cancer Lab at IRB Barcelona.We expect this study to have a big impact on the scientific community and to further advances in metastasis research, and we hope to be able to validate the potential of CD36 as an anti-metastasis treatment. Things like this dont happen every day.The team is now working with researchers in the UK to develop antibody-based treatments that work against CD36 for a range of cancers. If successful, they believe a new drug could be available in five to 10 years. IBTimes VideoRelated VideosMore videos Play VideoPlayMute0:00/0:00Loaded: 0%0:00Progress: 0%Stream TypeLIVE0:00?Playback Rate1xChaptersChaptersDescriptionsdescriptions off, selectedSubtitlessubtitles settings, opens subtitles settings dialogsubtitles off, selectedAudio TrackFullscreenThis is a modal window.The media could not be loaded, either because the server or network failed or because the format is not supported.Beginning of dialog window. Escape will cancel and close the window.TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal DialogEnd of dialog window. COPY LINKAD Loading … Drug that stops the spread of cancer has been developed Close
Share Who can figure out the true meaning of “covfefe” ??? Enjoy!— Donald J. Trump (@realDonaldTrump) May 31, 2017Twitter created a Moment to showcase all of the #covfefe tweets that have been rolling in from fellow politicians, comedians, news writers, and the general Twitter-verse. The Merriam-Webster dictionary shows no results for the word “covfefe”, so we’ll just have to see if the President reveals the definition in future tweets. what makes me saddest is that I know I’ll never write anything funnier than #covfefe— Jimmy Kimmel (@jimmykimmel) May 31, 2017 You don’t know what you got till it’s #Covfefe. pic.twitter.com/zs0KDbsMvO— Comedy Central (@ComedyCentral) May 31, 2017 Really sad I missed all the “covfefe” covfefe.— Gabriel Gundacker (@gabegundacker) May 31, 2017As for now, we’ll enjoy these tweets and say cheers to covfefe! It began in the early hours of the morning with a single tweet from the President of the United States: “Despite the constant negative press covfefe.”Now hours later, the tweet has been deleted, but many still scratch their heads in question over Trump’s mysterious vocabulary.What in the world is a covfefe?This morning, the President tweeted in response to the confusion.
Photo: Courtesy of Texas CentralPart of the high-speed rail line connecting Houston and Dallas would be built along Hempstead Road and, Texas Central, the company in charge of the project estimates it could create 1,000 permanent jobs.Paul Marrack owns about three acres in a far corner of northwest Harris County. He and his wife are restoring a historic farmhouse and they plan to retire there. Their property is also along the bullet train’s proposed route.Last year, Marrack said they started hearing from Texas Central, the private company developing the rail line.“We received a letter saying we were going to be referred to attorneys,” said Marrack. “And we were eventually sued to allow them to survey our property.”Marrack said Texas Central has since backed off on its legal action. He added the company also made an offer to buy the property but they have no desire to sell it. His concern now is that Texas Central will now try to use eminent domain authority to seize that land.Texas Central V-P Holly Reed maintains they can use eminent domain because of their status as a railroad. But critics of the project contend the company doesn’t have that authority because they’re currently not running an active rail line.As for their efforts to acquire property, Reed explained they’re now trying a more personal approach with landowners.“It would be a last resort to go through the court process,” said Reed.Texas Central is touting the high-speed train as an alternative to crowded freeways and airports. They said it will get riders between Houston and Dallas in 90 minutes with a stop midway near College Station.The company adds the rail line will be built entirely with private money while providing hundreds of new jobs. But those fighting the project fear it would eventually need taxpayer funding.Paul Marrack said he also questions whether the bullet train would to anything to help ease the region’s traffic woes.“At the present time Texas does not have the population density that will support high-speed rail,” said Marrack. “It also does not address the need for mitigation of traffic congestion in Houston or Harris County.”The Federal Railroad Administration is currently taking public comment as part of a draft environmental impact statement. They’ve been holding meetings along the train’s proposed route and they’re having one Monday night in northwest Harris County. It’s at Woodard Elementary School in Cypress and it starts at 6:00 p.m. Listen Share 00:00 /00:59 X To embed this piece of audio in your site, please use this code:
5 min read Growing a business sometimes requires thinking outside the box. November 17, 2014 The Internet is set for another revolution, much like the smartphone explosion of the 2000s. This revolution, the “Internet of Things” (IoT), will connect physical devices, such as air conditioners, appliances and lights to the Internet.The IoT is generating particularly widespread interest due to its projected growth from $33 billion in 2013 to $71 billion in 2018. Like technology revolutions of the past, much of the market will be captured by new companies with innovative products.Related: The 7 Most Useful Smart Home DevicesWe see connected-living startups pop up almost daily, but there are a few things that truly set successful IoT startups apart. So, how can you position your business for IoT success? Here are our top five tips:1. Ensure your device tells a “story.”Your product needs to tell a clear story that can both stand alone and also work well with other services. Consumers need to understand what specific need this product will serve, in their language.The “connected lifestyle” is really a grouping of these individual stories — a novel — that work better together. However, average consumers rarely walk into Best Buy intending to purchase a full suite of connected products all at once. Instead, they focus on one need at a time.The best way to handle this? Make sure that your product’s initial value proposition is crystal clear.The Zen thermostat is a good example. Its initial use case was clear from the beginning: a simple thermostat that connects to the Internet. This clear value proposition coupled with the fact that setup was easy and the product already had an established team behind it (fact: Indiegogo campaigns run by two or more people raise 94 percent more money than campaigns by single individuals), made it a desirable and well-designed campaign from the gate — attracting both consumers and press.2. Plan your compatibility roadmap from day one. Customers don’t want to invest in dead-end technology. They may not even fully understand the concept of the IoT when they purchase a connected device, but consumers have begun learning the value of combining several IoT devices together to increase their overall usefulness.What many don’t know, though, is that multiple standards exist and that not all devices speak the same “language.” Thus, it’s critical that your product plays nicely with other devices and services.3. Mentorship is even more important than you think.Every connected product requires expertise in many different domains: hardware layout, standards interoperability, industrial design, distribution strategy and many more. Leveraging industry mentors will help you make the best product possible.Related: Why U.S. Innovation Needs China to Achieve the Next Technology Mega-TrendMentorships can come in many forms: guidance through a crowdsourcing campaign, assistance with radio frequency design, navigation through complex certifications, and advice on distribution channel selection. Look to companies such as platform providers, chip manufacturers and business partners for this mentorship.For example, you should know the difference between Zigbee and Z-Wave, and what each standard can offer in terms of distribution channels and strategic partnerships. Rather than relying solely on technical issues, startups should think through these types of implications to guide their connectivity decision. Mentors can help you navigate these multi-faceted issues.4. Have a plan for handling privacy, security and data from the beginning.Life is made better by sharing information, but as we share more and more data, you need to know how you’re going to protect it. Even technology goliaths have made privacy missteps, causing reduced consumer confidence and lower sales volumes.This is certainly another area where mentorship can lend a hand. Partners can also accelerate your time to market by providing robust, safe, proven infrastructures that your devices can leverage.5. Assume the person setting up your product knows little about technology.The average consumer will not take the time to learn about technology in order to use a new device. Customers purchase IoT devices to make their lives easier, not more complex, so it’s important to ensure you are catering to novices, not early adopters. One of the most critical things to simplify and streamline: the set up of your connected device.While it is most important to cater to the average consumer, technology enthusiasts are often early adopters. Since they fuel the early phases of your growth, it is also important to provide them with access to advanced configuration, customization and other features. Just don’t let those tech-focused features take center stage.The future awaits.Historically, upstart companies have had huge opportunities during similar technological upheavals such as the industrial revolution, the introduction of the Internet and the propagation of smartphones.Consider the histories of John Deere, Oracle and Google. All of these companies grew exponentially due to technological shifts like the one we’re seeing with the Internet of Things. Give your company the best opportunity to take advantage of this huge market expansion by keeping these tips in mind.Related: 5 Steps the ‘Smart’ Home Industry Must Take to Develop a Consumer Market Free Webinar | Sept. 9: The Entrepreneur’s Playbook for Going Global Register Now » Opinions expressed by Entrepreneur contributors are their own.